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Lisuride
go.drugbank.com/drugs/DB00589ApprovedAn ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).
Synonyms: N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylureaCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeOMS906
go.drugbank.com/drugs/DB17722InvestigationalOMS906 is a humanized Igg4 monoclonal antibody against mannan-binding lectin-associated serine protease-3 (MASP-3) currently being developed by Omeros.
Seliforant
go.drugbank.com/drugs/DB15220InvestigationalSeliforant is under investigation in clinical trial NCT01260753 (Proof of Activity Study of UR-63325 in Allergic Rhinitis Induced by Nasal Challenge).
NN344
go.drugbank.com/drugs/DB05115ExperimentalNN344 is a neutral, soluble long-acting human insulin analogue with 24 hour coverage by once daily injection. NN344 has a very flat and predictable action profile.
Imipramine oxide
go.drugbank.com/drugs/DB13782ExperimentalSynonyms: Imipramine N-oxideCategories: Non-Selective Monoamine Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeLofepramine
go.drugbank.com/drugs/DB13411ExperimentalCategories: Non-Selective Monoamine Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromePhenylacetic acid
go.drugbank.com/drugs/DB09269ApprovedBecause it is used in the illicit production of phenylacetone (used in the manufacture of substituted amphetamines), it is subject to controls in countries including the United States and China.
scyllo-inositol
go.drugbank.com/drugs/DB03106InvestigationalAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man.
Pramiracetam
go.drugbank.com/drugs/DB13247ApprovedPramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression [L5470].
Zelicapavir
go.drugbank.com/drugs/DB21662InvestigationalZelicapavir is under investigation in clinical trial NCT06601192 (A Study to Investigate the Effects of Zelicapavir (EDP-938) on QTc Interval in Healthy Adults).