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Displaying results 5451 - 5460 of 10000 in total
  1. Drug

    5-androstenedione

    go.drugbank.com/drugs/DB01456
    ExperimentalIllicit

    In the United States, the Controlled Substance Act is inclusive to anabolic steroids and their precursors. … Apart from the positioning of a carbon-carbon double bond, its structure is similar to [4-androstenedione], which is a prohormone which is naturally produced in the body by the adrenal glands and gonads

  2. Drug

    Eliapixant

    go.drugbank.com/drugs/DB21465
    Investigational

    The usage of the INN stem '-pixant' in the name indicates that Eliapixant is a purinoreceptor (P2X) antagonist. … Pill (Placebo) and Elagolix in Women Suffering From Pain Related to a Condition Where the Tissue That Usually Grows Inside the Womb Grows Outside of the Womb).

  3. Drug

    Inosinic Acid

    go.drugbank.com/drugs/DB04566
    Investigational

    A purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety.

  4. Drug

    Horse chestnut

    go.drugbank.com/drugs/DB13195
    Investigational

    The active component of this pure extract is escin, or aescin, that promotes blood circulation through the veins and reduces swelling and inflammation of the legs. … These seeds are processed to remove the toxic component, resulting in purified horse chestnut seed extract (HCSE) [A27200].

  5. Drug

    Sulfisoxazole

    go.drugbank.com/drugs/DB00263
    ApprovedVet approved

    A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

  6. Drug

    XL784

    go.drugbank.com/drugs/DB04991
    Investigational

    XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied metalloprotease inhibitors. … XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation.

  7. Target

    Protein-tyrosine kinase 2-beta

    go.drugbank.com/bio_entities/BE0000871
    TargetHumans

    Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. … Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.

    Synonyms: Calcium-regulated non-receptor proline-rich tyrosine kinase
  8. Drug

    Human Umbilical Cord Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15726
    Investigational

    The cells are extracted by either the explant or the enzymatic digestion method, though neither method has been characterized as the ‘standard’ thus far. … The cord lining of the UC is generally isolated with the explant method -- resulting in two kinds of MSCs: cord lining mesenchymal stem cells (CLMC), which are used to aid in burn and diabetic ulcer wound

  9. Drug

    Merimepodib

    go.drugbank.com/drugs/DB04862
    Investigational

    Merimepodib is orally bioavailable and inhibits the proliferation of primary human, mouse, rat, and dog lymphocytes at concentrations of approximately 100 nM.

  10. Drug

    Aluminum zirconium tetrachlorohydrex gly

    go.drugbank.com/drugs/DB11149
    ApprovedWithdrawn

    Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.

    Products: Oscar De LA Renta, So De LA Renta Antiperspirant Deodorant, Oscar for Men, Oscar De LA Renta