Search

Displaying results 541 - 550 of 10000 in total
  1. Drug

    Metronidazole

    go.drugbank.com/drugs/DB00916
    ApprovedInvestigational

    a wide variety of infections. … Metronidazole is a commonly used antibiotic, belonging to the nitroimidazole class of antibiotics.

    Mixtures: NEO-PENOTRAN FORTE-L 750 MG/ 200 MG/ 100 MG OVUL, 7 ADET, NOVO-VULOTRAN FORTE L 750 MG/200 MG/100 MG VAJİNAL OVÜL ,7 OVÜLCategories: Heterocyclic Compounds, 1-Ring, Antibacterials for Systemic Use
  2. Target

    Monocarboxylate transporter 10

    go.drugbank.com/bio_entities/BE0003654
    TransporterHumans

    Sodium- and proton-independent thyroid hormones and aromatic acids transporter (PubMed:11827462, PubMed:18337592, PubMed:28754537). Mediates both uptake and efflux of 3,5,3'-triiodothyronine (T3) and 3,5,3',5'-tetraiodothyronine (T4) wit...

    Polypeptides: Monocarboxylate transporter 10Synonyms: MCT 10, Solute carrier family 16 member 10
  3. Drug

    Methadone

    go.drugbank.com/drugs/DB00333
    ApprovedInvestigational

    Methadone is a potent synthetic analgesic that works as a full µ-opioid receptor (MOR) agonist and N-methyl-d-aspartate (NMDA) receptor antagonist. … As a full MOR agonist, methadone mimics the natural effects of the body's opioids, endorphins, and enkephalins through the release of neurotransmitters involved in pain transmission.

    Products: Methasan 10 mg-Tabletten, METHADOSE® 10 MG TABLETAS
  4. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). … Nitroprusside is often administered intravenously to patients who are experiencing a hypertensive emergency.

    Categories: Compounds used in a research, industrial, or household settingProducts: NITROPRUSIATO DE SODIO SOLUCION INYECTABLE POR 2 ML, NITROPRUSIATO DE SODIO 50 MG/2 ML INYECTABLE
  5. Drug

    Iopromide

    go.drugbank.com/drugs/DB09156
    Approved

    Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. … favorable safety profile, with only 0.7% of patients in a 2 years study experiencing adverse events.

    Categories: Compounds used in a research, industrial, or household settingProducts: RAVİSTU 300 MG I/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 100 ML, İOPOLİMİD 370 MG I/ML ENJEKSİYONLUK ÇÖZELTİ, 100 ML
  6. Drug

    Hydroxyzine

    go.drugbank.com/drugs/DB00557
    ApprovedInvestigational

    Hydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. … [A1257,A187589] It was first developed in 1955,[A189726] and has since remained a relatively common treatment for allergic conditions such as pruritus, urticaria, dermatoses, and histamine-mediated pruritus

    Mixtures: ATARAX FILM TABLET, 30 ADET, ATARAX FILM TABLET, 30 ADETCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    [L32995] Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery. … [L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline.

    Synonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)International brands: Vomex A
  8. Drug

    Dolutegravir

    go.drugbank.com/drugs/DB08930
    ApprovedInvestigational

    [L1035] On November 21, 2017, dolutegravir, in combination with rilpivirine, was approved as part of the first complete treatment regimen with only two drugs for the treatment of adults with HIV-1 named … [A31342] Dolutegravir was developed by ViiV Healthcare and FDA-approved on August 12, 2013.

    Mixtures: TRIUMEQ 50 MG/600 MG/300 MG FILM KAPLI TABLET,90 FILM KAPLI TABLET, TRIUMEQ® 50 MG / 600 MG / 300 MGCategories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-Ring
  9. Drug

    Calcitriol

    go.drugbank.com/drugs/DB00136
    ApprovedInvestigationalNutraceutical

    Calcitriol is marketed under various trade names including Rocaltrol (Roche), Calcijex (Abbott) and Decostriol (Mibe, Jesalis). … [DB00146] undergoes hydroxylation to form calcitriol via 1α-hydroxylase (CYP27B1) activity [A26353]. Calcitriol is considered to be the most potent metabolite of vitamin D in humans [A3366].

    Synonyms: 1α,25(OH)2D3, (1α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triolCategories: Antipsoriatics for Topical Use
  10. Drug

    Levobupivacaine

    go.drugbank.com/drugs/DB01002
    ApprovedInvestigationalWithdrawn

    It is approximately 13 per cent less potent (by molarity) than racemic bupivacaine.Levobupivacaine is indicated for local anaesthesia including infiltration, nerve block, ophthalmic, epidural and intrathecal … In particular, the specific levobupivacaine enantiomer is a worthwhile pursuit because it demonstrates less vasodilation and possesses a greater length of action in comparison to bupivacaine.

    Synonyms: L-(-)-1-Butyl-2',6'-pipecoloxylidide, (S)-1-butyl-2',6'-pipecoloxylidideProducts: CHIROCAINE 50 MG/10 ML INF. ICIN KONS. COZELTI ICEREN 10ML X 10 AMPUL, CHIROCAINE 25 MG/10 ML INF. ICIN KONS. COZELTI ICEREN 10ML X 10 AMPUL