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Davesomeran
go.drugbank.com/drugs/DB17091ApprovedInvestigationalDavesomeran is a mRNA vaccine used in conjunction with [elasomeran] as part of the Moderna Bivalent COVID-19 vaccine. … [L43882] In October 22nd 2022, the FDA approved the Moderna Bivalent Vaccine as a booster in patients 6 years or older, administered at least 2 months after completion of primary vaccination or receipt
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Chromium
go.drugbank.com/drugs/DB11136ApprovedInvestigationalChromium chloride is available as an intravenous injection for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN) [FDA Label]. … Trivalent chromium (Cr(III)) ion is considered to be an essential dietary trace element as it is involved in metabolism of blood glucose, regulation of insulin resistance and metabolism of lipids.
Mixtures: Complete One-A-day - Tab, Complete One A Day TabProducts: Chelated Chromium Gtf 500mcg TabOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexAmiloride
go.drugbank.com/drugs/DB00594ApprovedInvestigationalA pyrazine compound inhibiting sodium reabsorption through sodium channels in renal epithelial cells. … (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
Mixtures: Aa-amilzide, AMILORID HCT ALSulfamerazine
go.drugbank.com/drugs/DB01581ApprovedVet approvedWithdrawnA sulfanilamide that is used as an antibacterial agent.
Mixtures: Trisulfaminic TabNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors.
Mixtures: TILIDIN AL COMP, TILIDIN AL COMPFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigationalantihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation. … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Products: FEXU AD ®Calcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt is a salt that is solid at room temperature, and it behaves as a typical ionic halide. … It can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers.
Mixtures: Ringer-Lactat nach Hartmann B.Braun Infusionslösung, Ringer-Lactat nach Hartmann NORIDEM InfusionslösungRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food.
Products: Ag-rivaroxaban, Nb-rivaroxabanAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalA biosimilar marketed as Hyrimoz, a high-concentration formulation of adalimumab, is also available.[L45643,L45818]. … [A39983] This drug is frequently known as _Humira_. It is produced by recombinant DNA technology using a mammalian cell expression system.
Products: HUMIRA® AC