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Displaying results 5491 - 5500 of 10000 in total
  1. Drug

    Sabiporide

    go.drugbank.com/drugs/DB21244
    Experimental

    Sabiporide is a small molecule drug. The usage of the INN stem '-poride' in the name indicates that Sabiporide is a Na+/H+ antiport inhibitor. … Sabiporide has a monoisotopic molecular weight of 408.15 Da.

  2. Drug

    Tozorakimab

    go.drugbank.com/drugs/DB16473
    Investigational

    Tozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions. … moderate-to-severe asthma), NCT04170543 (completed with results; diabetic kidney disease), NCT05624450 (recruiting; viral lung infection requiring supplemental oxygen), NCT05742802 (recruiting; long-term study in

  3. Drug

    Fidexaban

    go.drugbank.com/drugs/DB19562
    Experimental

    Fidexaban is a small molecule drug. The usage of the INN stem '-xaban' in the name indicates that Fidexaban is a blood coagulation factor XA​ inhibitor, antithrombotic. … Fidexaban has a monoisotopic molecular weight of 526.18 Da.

  4. Drug

    Bucetin

    go.drugbank.com/drugs/DB13278
    ApprovedWithdrawn

    Bucetin is an analgesic and antipyretic medication which was approved for use in Germany but was withdrawn from the market in 1986 due to renal toxicity caused by the medication.[A175636]

  5. Drug

    Hydrogen fluoride

    go.drugbank.com/drugs/DB11072
    ApprovedInvestigational

    It is used as a chemical reagent in several industrial processes such as oil refinery. It is also used as etchant, cleaning agent, and a reagent to dissolve oxides and silicates. … Hydrogen fluoride (Hydrofluoric acid) is a weak acid that is a precursor to almost all fluorine compounds, including pharmaceuticals such as [DB00472] (Prozac).

    Mixtures: Oral-B Minute-Foam Orang-A-Tangy
  6. Drug

    Pargyline

    go.drugbank.com/drugs/DB01626
    Approved

    Pargyline is a monoamine oxidase inhibitor with antihypertensive properties.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  7. Drug

    Mequitazine

    go.drugbank.com/drugs/DB01071
    Investigational

    Mequitazine is a histamine H1 antagonist (antihistamine). … It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract.

  8. Drug

    Danvatirsen

    go.drugbank.com/drugs/DB14825
    Investigational

    Danvatirsen is under investigation in clinical trial NCT03334617 (Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.).

  9. Drug

    TPI-ASM8

    go.drugbank.com/drugs/DB05572
    Investigational

    TPI-ASM8 was under investigation in clinical trials NCT00822861, NCT01158898, NCT00402948, and NCT00550797, all for the treatment of Asthma.

  10. Drug

    Zimelidine

    go.drugbank.com/drugs/DB04832
    ApprovedWithdrawn

    Additionally, zimelidine was charged to cause an increase in suicidal ideation and/or attempts among depressive patients. … Zimelidine has been banned worldwide due to serious, sometimes fatal, cases of central and/or peripheral neuropathy known as Guillain-Barré syndrome and due to a peculiar hypersensitivity reaction involving

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates