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Displaying results 5501 - 5510 of 10000 in total
  1. Drug

    Etynodiol

    go.drugbank.com/drugs/DB13866
    Experimental

    Etynodiol (INN), or ethynodiol (BAN) is a steroidal progestin related to norethisterone which was never marketed. … While etynodiol is sometimes used as a synonym for etynodiol diacetate, it usually refers to etynodiol diacetate (see [DB00823]), not etynodiol.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: (3β,17α)-19-Norpregn-4-en-20-yne-3,17-diol, 17α-Ethynyl-19-norandrost-4-ene-3β,17β-diol
  2. Drug

    Alprostadil

    go.drugbank.com/drugs/DB00770
    ApprovedInvestigational

    Alprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … [A257068,A257088] Alprostadil is also used in neonatal patients with congenital heart defects that depend on a patent ductus for survival until corrective or palliative surgery can be performed.

    Categories: Prostaglandins ESynonyms: (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, PGE-1
  3. Drug

    20-Hydroxyecdysone

    go.drugbank.com/drugs/DB16935
    Investigational

    Synonyms: Cholest-7-en-6-one, 2,3,14,20,22,25-hexahydroxy-, (2.beta.,3.beta.,5.beta.,22r)-, Polypodin a
  4. Drug

    Pucotenlimab

    go.drugbank.com/drugs/DB17552
    ApprovedInvestigational

    Pucotenlimab is a recombinant humanized anti-PD-1 monoclonal antibody. It received its first global approval in China in July 2022 for the treatment of solid tumours.

    Synonyms: Immunoglobulin g4 (252-theronine,306-proline,432-alanine), anti-(human programmed cell death 1) (human-mus musculus monoclonal hx008 .gamma.4-chain), disulfide with human-mus musculus monoclonal hx008, Humanized pd-1 blocking antibody hx-008
  5. Drug

    Tryptophanamide

    go.drugbank.com/drugs/DB04537
    Experimental

    Synonyms: (S)-alpha-Amino-1H-indole-3-propionamide, L-tryptophanamide
  6. Drug

    Oxfendazole

    go.drugbank.com/drugs/DB11446
    InvestigationalVet approved

    Oxfendazole is a sulfoxide metabolite of fenbendazole. This benzimidazole antihelminthic protects livestock from roundworm. strongyles, and pinworn.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole, 5-(phenylsulfinyl)-2-benzimidazolecarbamic acid methyl ester
  7. Drug

    8-oxo-dGMP

    go.drugbank.com/drugs/DB02023
    Experimental

    Synonyms: 2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid, 8-oxo-2'-deoxyguanosine-5'-monophosphateCategories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Ropinirole

    go.drugbank.com/drugs/DB00268
    ApprovedInvestigational

    Ropinirole, also known as _ReQuip_, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], [A174547]. … In 2008, the extended-release capsules of ropinirole were approved, allowing for less frequent dosing, therefore increased compliance, and offering a similar side effect profile and efficacy to previous

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: ROPINIROL AL 3 MG RET, ROPINIROL-NEURAX 3 MG
  9. Drug

    Tetramethylpyrazine nitrone

    go.drugbank.com/drugs/DB23609
    Investigational

    Synonyms: (Z)-N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDE, N-TERT-BUTYL-1-(3,5,6-TRIMETHYLPYRAZIN-2-YL)METHANIMINE OXIDECategories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Reproxalap

    go.drugbank.com/drugs/DB16688
    Investigational

    Reproxalap (previously ADX 102 or NS-2) is a small molecule inhibitor being developed by Aldeyra Therapeutics investigated against dry eye disease, allergic conjunctivitis, noninfectious anterior uveitis … [L32990] NS-2 has orphan drug status due to it being investigated for treatment of Sjogren-Larsson syndrome.[L32990]

    Categories: Heterocyclic Compounds, 2-RingSynonyms: NS-2