Search

Displaying results 5521 - 5530 of 8697 in total
  1. Drug

    Androstenedione

    go.drugbank.com/drugs/DB01536
    IllicitInvestigational

    Depending on the tissue type, androstenedione can serve as a precursor to testosterone as well as estrone and estradiol.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    D-Tryptophan

    go.drugbank.com/drugs/DB03225
    Experimental

    The D-stereoisomer is occasionally found in naturally produced peptides (for example, the marine venom peptide contryphan). … The distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats.

  3. Drug

    Pentolinium

    go.drugbank.com/drugs/DB01090
    Approved

    Pentolinium is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.

  4. Target

    Nectin-4

    go.drugbank.com/bio_entities/BE0009798
    TargetHumans

    Does not act as receptor for alpha-herpesvirus entry into cells

    Synonyms: Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4
  5. Target

    NKG2-A/NKG2-B type II integral membrane protein

    go.drugbank.com/bio_entities/BE0010560
    TargetHumans

    Immune inhibitory receptor involved in self-nonself discrimination. … In HLA-E-rich tumor microenvironment, acts as an immune inhibitory checkpoint and may contribute to progressive loss of effector functions of NK cells and tumor-specific T cells, a state known as cell

    Synonyms: NK cell receptor A, NKG2-A/B-activating NK receptorFunction: HLA-E specific inhibitory MHC class Ib receptor activity
  6. Drug

    EGT-201

    go.drugbank.com/drugs/DB17648
    Experimental

    Developed by Esteve Pharmaceuticals, it is being investigated for Sanfilippo syndrome type B.[L45939] … EGT-201 is an adeno-associated viral vector serotype 9 (AAV9) vector-based gene therapy consisting of the alpha-N-acetyglucosaminidase (NAGLU) transgene.

  7. Drug

    MK-0354

    go.drugbank.com/drugs/DB05939
    Investigational

    MK-0354, is an orally administered drug candidate under development by Merck for the treatment of atherosclerosis and related disorders. … It targets G protein-coupled receptor, or GPCR, that have the potential to regulate plasma lipid profiles, including HDL, or the good cholesterol, similar to the therapeutic action of niacin.

  8. Drug

    Carotuximab

    go.drugbank.com/drugs/DB06322
    Investigational

  9. Drug

    Pozanicline

    go.drugbank.com/drugs/DB05458
    Investigational

    ABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity

  10. Drug

    HGTV-43

    go.drugbank.com/drugs/DB05807
    Experimental

    HGTV43 is an anti-sense treatment designed to produce T cells that are genetically resistant to HIV infection.