Search

Displaying results 5551 - 5560 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/20:4(5Z,8Z,11Z,14Z)/18:2(9Z,12Z))

    smpdb.ca/view/SMP0250629
    Metabolic

    Last, cardiolipin synthase catalyzes the synthesis of cardiolipin by transferring a phosphatidyl group from a second CDP-diacylglycerol to PG. It requires a divalent metal cation cofactor.

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
  2. Drug

    Hepatitis B Vaccine (Recombinant)

    go.drugbank.com/drugs/DB11627
    ApprovedInvestigationalWithdrawn

    Hepatitis B Vaccine is an ingredient in the EMA-withdrawn product Quintanrix. It is marketed in Canada as Engerix B. It is also a part of Twinrix (Hep A/Hep B vaccine) available also in Canada. … In Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier

    Synonyms: Hepatitis B antigen, Hepatitis B VaccineSalts: Hepatitis B virus subtype ADW HBSAG surface protein antigen, Hepatitis B virus subtype ADW2 HBSAG surface protein antigen
  3. Drug

    Dabrafenib

    go.drugbank.com/drugs/DB08912
    ApprovedInvestigational

    Dabrafenib mesylate (Tafinlar) is a reversible ATP-competitive kinase inhibitor and targets the MAPK pathway. … [L41955] In May 2018, Tafinlar (dabrafenib), in combination with Mekinist ([DB08911]), was approved to treat anaplastic thyroid cancer caused by an abnormal BRAF V600E gene.[L41955]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C19 Substrates with a Narrow Therapeutic IndexProducts: TAFINLAR®75 MG CÁPSULAS DURAS, TAFINLAR® 50 MG CÁPSULAS DURAS
  4. Drug

    Methyl aminolevulinate

    go.drugbank.com/drugs/DB00992
    ApprovedInvestigational

    Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

    Categories: Sensitizers Used in Photodynamic/radiation TherapySynonyms: methyl 5-aminolevulinate, methyl δ-aminolevulinate
  5. Pathway

    Phosphatidylcholine Biosynthesis PC(18:4(6Z,9Z,12Z,15Z)/20:4(8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0014552
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. … PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
    Enzymes: Choline-phosphate cytidylyltransferase A
  6. Pathway

    Phosphatidylcholine Biosynthesis PC(20:4(5Z,8Z,11Z,14Z)/22:4(7Z,10Z,13Z,16Z))

    smpdb.ca/view/SMP0014731
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. … PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
    Enzymes: Choline-phosphate cytidylyltransferase A
  7. Pathway

    Phosphatidylcholine Biosynthesis PC(20:4(8Z,11Z,14Z,17Z)/20:4(5Z,8Z,11Z,14Z))

    smpdb.ca/view/SMP0014754
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. … PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
    Enzymes: Choline-phosphate cytidylyltransferase A
  8. Pathway

    Phosphatidylcholine Biosynthesis PC(20:4(8Z,11Z,14Z,17Z)/20:4(8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0014755
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. … PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
    Enzymes: Choline-phosphate cytidylyltransferase A
  9. Pathway

    Phosphatidylcholine Biosynthesis PC(22:4(7Z,10Z,13Z,16Z)/20:4(8Z,11Z,14Z,17Z))

    smpdb.ca/view/SMP0014900
    Metabolic

    Phosphatidylcholines (PC) are a class of phospholipids that incorporate a phosphocholine headgroup into a diacylglycerol backbone. … PEMT uses S-adenosyl-L-methionine as a methyl donor.

    Drugs: Ademetionine · Choline · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · N,N,N-Trimethyl-2-(phosphonooxy)ethanaminium +2 more
    Enzymes: Choline-phosphate cytidylyltransferase A
  10. Pathway

    Phosphatidylethanolamine Biosynthesis PE(18:4(6Z,9Z,12Z,15Z)/20:4(5Z,8Z,11Z,14Z))

    smpdb.ca/view/SMP0015391
    Metabolic

    Phosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. … Phosphatidylserine, itself, is synthesized using a base-exchange reaction with phosphatidylcholine.

    Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 more