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Displaying results 5581 - 5590 of 10000 in total
  1. Drug

    Alferminogene tadenovec

    go.drugbank.com/drugs/DB05306
    Investigational

    Alferminogene tadenovec, Cardium’s lead product candidate, is being developed for the potential treatment of myocardial ischemia that gives rise to angina symptoms associated with coronary heart disease … Alferminogene tadenovec represents a new therapeutic class of biologics designed to promote angiogenesis and thereby improve blood flow following a one-time intracoronary administration from a standard

    Synonyms: Ad5FGF-4
  2. Drug

    Colchiceine

    go.drugbank.com/drugs/DB15534
    Approved

    Colchiceine is one of several metabolites of the anti-gout medication [colchicine].[A192714]

    Synonyms: O-Demethylcolchicine, 10-O-demethylcolchicine
  3. Drug

    Guanosine-5'-Diphosphate

    go.drugbank.com/drugs/DB04315
    Experimental

    A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. [PubChem]

    Synonyms: Guanosine-5'-Diphosphate
  4. Drug

    RTA 744

    go.drugbank.com/drugs/DB05920
    Investigational

    RTA 744 is a novel anthracycline derivative that crosses the blood-brain barrier and shows significant potential for the treatment of primary and metastatic brain cancers. … Anthracyclines are one of the most broadly used and effective classes of cancer therapies; however, they are not used to treat brain cancers because current therapies do not cross the blood-brain barrier

  5. Drug

    Metampicillin

    go.drugbank.com/drugs/DB13836
    Experimental

    Metampicillin is a penicillin antibiotic prepared by the reaction of ampicillin with formaldehyde. It is hydrolysed in aqueous solution to form ampicillin. … Hydrolysis is rapid under acid conditions like the stomach.

    Categories: Penicillin G, Heterocyclic Compounds, 2-Ring
  6. Drug

    INM004

    go.drugbank.com/drugs/DB17791
    Investigational

    INM004, a Neutralizing Equine Anti-Stx Hyperimmune Immunoglobulin F(Ab')2 Fragment, is currently being investigated to treat Shiga-toxin producing bacterial infection relating to the prevention of hemolytic

    Synonyms: Anti-Shiga toxin hyperimmune equine immunoglobulin F(ab')2 fragment, Neutralizing equine anti-Stx hyperimmune immunoglobulin F(ab')2 fragment
  7. Drug

    Ciglitazone

    go.drugbank.com/drugs/DB09201
    Experimental

    Developed by Takeda Pharmaceuticals in the early 1980s, it is considered the prototypical compound for the thiazolidinedione class. … Ciglitazone was never used as a medication, but it sparked interest in the effects of thiazolidinediones.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Inhibitors
  8. Drug

    Satavaptan

    go.drugbank.com/drugs/DB14923
    Investigational

    Satavaptan is under investigation in clinical trial NCT00359437 (Satavaptan in the Prevention of Ascites Recurrence in Patients With Ascites Due to Cirrhosis of the Liver).

    Categories: Heterocyclic Compounds, 1-Ring
  9. Drug

    7,8-dihydrobiopterin

    go.drugbank.com/drugs/DB04400
    Experimental

    7,8-Dihydrobiopterin is an inhibitor of the enzyme dihydroneopterin aldolase (DHNA), which catalyzes the conversion of 7,8-Dihydrobiopterin to 6-hydroxymethyl-7,8-dihydropterin and glycolaldehyde.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: L-erythro-q-Dihydrobiopterin, q-BH2
  10. Drug

    Tecadenoson

    go.drugbank.com/drugs/DB04954
    Investigational

    Tecadenoson is a novel selective A1 adenosine receptor agonist that is currently being evaluated for the conversion of paroxysmal supraventricular tachycardia (PSVT) to sinus rhythm. … It is being developed by CV Therapeutics, Inc.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring