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Displaying results 5581 - 5590 of 10000 in total
  1. Drug

    Siltuximab

    go.drugbank.com/drugs/DB09036
    ApprovedInvestigational

    It is administered as a 1 hour intravenous infusion every 3 weeks. … Siltuximab is a chimeric (human-mouse) monoclonal immunoglobulin G1-kappa antibody produced in a Chinese hamster ovary (CHO) cell line by recombinant DNA technology.

  2. Drug

    Shark liver oil

    go.drugbank.com/drugs/DB11088
    Approved

    Shark oil is a rich source of alkylglycerols and squalene, with relatively low amounts of n-3 polyunsaturated fatty acids. … The potential benefit of shark oil has been experimented in different therapeutic implications, where it is claimed to improve immune responses and exert an antitumor activity.

  3. Drug

    Zebularine

    go.drugbank.com/drugs/DB03068
    Experimental

    A chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates.

  4. Drug

    Ethyl pyruvate

    go.drugbank.com/drugs/DB05869
    Investigational

    CTI-01 (ethyl pyruvate) is a novel anti-inflammatory agent for the treatment of critical inflammatory conditions. … CTI-01 shows a potent anti-inflammatory and tissue protection activity in multiple animal models of disease including pancreatitis, ischemia-reperfusion injury, sepsis, renal injury and endotoxemia.

  5. Drug

    Elinzanetant

    go.drugbank.com/drugs/DB18968
    ApprovedInvestigational

    Elinzanetant is a non-hormonal, selective, dual neurokinin 1 (NK-1) and 3 (NK-3) receptor antagonist. … [L53798] By blocking receptor signaling on kisspeptin/neurokinin B/dynorphin (KNDy) neurons, which are hyperactivated due to estrogen decline in menopause, elinzanetant modulates neuronal activity involved

    Categories: Neurokinin 3 Receptor Antagonist, Neurokinin-1 Receptor Antagonists
  6. Drug

    Neramexane

    go.drugbank.com/drugs/DB04926
    Investigational

    Neramexane is a low-to-moderate affinity uncompetitive NMDA receptor antagonist.

  7. Drug

    Isunakinra

    go.drugbank.com/drugs/DB12373
    Investigational

    Isunakinra has been investigated for the treatment of Dry Eye and Allergic Conjunctivitis (AC).

    Categories: Interleukin-1 Receptor Antagonist
  8. Drug

    Amfenac

    go.drugbank.com/drugs/DB15911
    Investigational

    Amfenac is an arylacetic acid derivative and a non0steroidal anti-inflammatory agent.[A275203, A275208]

  9. Drug

    Tildacerfont

    go.drugbank.com/drugs/DB18545
    Investigational

    Tildacerfont is a corticotropin-releasing factor receptor-1 antagonist containing an unfused thiazole ring

    Synonyms: Pyrazolo(1,5-a)pyrimidine, 3-(4-chloro-2-(4-morpholinyl)-5-thiazolyl)-7-(1-ethylpropyl)-2,5-dimethyl-pyrazolo(1,3-a)pyrimidine, 3-(5-chloro-2-morpholin-4-yl-thiazol-4-yl)-7-(1-ethyl-propyl)-2,5-dimethyl-pyrazolo(1,5-a)pyrimidine
  10. Drug

    ARCT-810

    go.drugbank.com/drugs/DB17683
    Investigational

    ARCT-810 is an mRNA replacement therapy that delivers ornithine transcarbamylase mRNA to hepatocytes.