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Displaying results 551 - 560 of 6949 in total
  1. Drug

    Trastuzumab duocarmazine

    go.drugbank.com/drugs/DB16342
    Investigational

    Trastuzumab duocarmazine is under investigation in clinical trial NCT03262935 (SYD985 vs. Physician's Choice in Participants With Her2-positive Locally Advanced or Metastatic Breast Cancer).

    Synonyms: Immunoglobulin g1-kappa, anti-(homo sapiens erbb2 (epidermal growth factor receptor 2, receptor tyrosineprotein kinase erbb-2, egfr2, her2, her-2, p185cerbb2, neu, cd340)), humanized monoclonal antibodyCategories: HER2 (Human Epidermal Growth Factor Receptor 2) inhibitors
  2. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. ...

    Mixtures: Sterile Diluent for Allergenic Extract, Sterile Diluent for Allergenic ExtractCategories: Sclerosing Agents for Local Injection
  3. Drug

    Afoxolaner

    go.drugbank.com/drugs/DB11369
    ExperimentalVet approved

    Mixtures: Nexgard Spectra 38mg/8mg Chewable Tablets for Dogs >7.5-15kg, Nexgard Spectra 9mg/2mg Chewable Tablets for Dogs 2-3.5kgProducts: NexGard 11mg chewable tablets for dogs 2-4kg, NexGard 136mg chewable tablets for dogs > 25-50kg
  4. Pathway

    Sphingolipid Signaling (Receptor)

    smpdb.ca/view/SMP0524344
    Signaling

    Through these receptor‑specific G protein couplings—spanning cAMP suppression, Ca²⁺ mobilization, PKC activation, Rho GTPase–driven cytoskeletal remodeling, and PI3K/Akt and MAPK pathways—S1P orchestrates

    Drugs: Nitric Oxide · Calcium · Magnesium cation
    Enzymes: Sphingosine 1-phosphate receptor 2, Sphingosine 1-phosphate receptor 4
  5. Drug

    Plantago seed

    go.drugbank.com/drugs/DB11097
    ApprovedInvestigational

    It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements.

    Mixtures: Metamucil Therapy for Regularity, Metamucil Therapy for RegularityProducts: Metamucil Therapy for Regularity, Metamucil Therapy for regularity
  6. Drug

    PBCAR20A

    go.drugbank.com/drugs/DB17189
    Investigational

    Synonyms: Allogeneic gene edited CD20-directed CAR (Chimeric Antigen Receptor) T cells
  7. Drug

    Becotatug

    go.drugbank.com/drugs/DB19069
    Investigational

    JMT101 in Combination With Osimertinib, Versus Cisplatin-pemetrexed in Participants With Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor

    Synonyms: Jmt101 (fully human monoclonal igg1 antibody targeting epidermal growth factor receptor (egfr)), Immunoglobulin G1, anti-(human epidermal growth factor receptor) (human-Mus musculus monoclonal JMT101 γ1-chain), disulfide with human-Mus musculus monoclonal JMT101 κ-chain, dimer
  8. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    [A176318] It is also used for its antipyretic effects, helping to reduce fever.[F4124] This drug was initially approved by the U.S. … [L5783] Confusion about dosing of this drug may be caused by the availability of different formulas, strengths, and dosage instructions for children of different ages.

    Mixtures: Only For HEADACHE, Stona for ChildrenInternational brands: Snaplets-FR
  9. Drug

    Vonlerolizumab

    go.drugbank.com/drugs/DB16352
    Investigational

    trial NCT03029832 (A Study of MOXR0916 in Combination With Atezolizumab Versus Atezolizumab Alone in Participants With Untreated Locally Advanced or Metastatic Urothelial Carcinoma Who Are Ineligible for

    Synonyms: Immunoglobulin g1-kappa, anti-(human tumor necrosis factor receptor superfamily member 4 (act35 antigen, ox40l receptor, cd134 antigen))humanized mouse monoclonal antibody: .gamma.1 heavy chain (1-447), Immunoglobulin g1-kappa, anti-(homo sapiens tnfrsf4(tumor necrosis factor receptor (tnfr) superfamily member 4, act35, ox40, cd134)), humanized monoclonal antibody
  10. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparatio...

    Categories: Agents for Dermatitis, Excluding CorticosteroidsProducts: PROGRAF CONCENTRATE FOR INFUSION 5 mg/ml, PROGRAF CONCENTRATE FOR INFUSION 5MG/ML