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Pyridoxine
go.drugbank.com/drugs/DB00165ApprovedInvestigationalNutraceuticalVet approvedPyridoxine is the 4-methanol form of vitamin B6, an important water-soluble vitamin that is naturally present in many foods. … It is also used in combination with [DB00366] (as the commercially available product Diclectin) for the treatment of nausea and vomiting in pregnancy.
Synonyms: 2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine, 3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridineMixtures: LYSOBACT 20 MG/10 MG PASTİL, 30 ADET, PRİLAM DR 10 MG/10 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADETSertindole
go.drugbank.com/drugs/DB06144ApprovedWithdrawnIt was first marketed in 1996 in several European countries before being withdrawn two years later because of numerous cardiac adverse effects. … It is a phenylindole derivative used in the treatment of schizophrenia.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-oneVerapamil
go.drugbank.com/drugs/DB00661ApprovedInvestigational[L8791] Verapamil is administered as a racemic mixture containing equal amounts of the S- and R-enantiomer, each of which is pharmacologically distinct - the S-enantiomer carries approximately 20-fold … into therapy in the early 1960s.
Mixtures: VERACOMB MR 180/2 MG KAPSÜL, 28 ADET, VERAPIN 180 MG/2 MG FILM KAPLI TABLET, 28 ADETCategories: MATE 2 Inhibitors, MATE 1 InhibitorsEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings … Unlike other classes of cholesterol-reducing compounds including statins and bile acid sequestrants, ezetimibe has a distinct mechanism of action involving the sterol transporter Niemann-Pick C1-Like 1
Mixtures: VYTORIN ® 10/20 MG, VYTORIN ® 10/20 MGCategories: Heterocyclic Compounds, 1-RingDimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigationalDimehydrinate was first described in the literature in 1949,[A233120] and patented in 1950. … [L32995] Early research into dimenhydrinate focused on its role as an antihistamine for urticaria; the treatment of motion sickness was an accidental discovery.
Synonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinateMixtures: Arlevert 20 mg/40 mg TablettenPantoprazole
go.drugbank.com/drugs/DB00213ApprovedInvestigationallonger than 24 hours. … Pantoprazole exerts its stomach acid-suppressing effects by preventing the final step in gastric acid production by covalently binding to sulfhydryl groups of cysteines found on the (H+, K+)-ATPase enzyme
Categories: 2-PyridinylmethylsulfinylbenzimidazolesProducts: PANTO 40 MG IV ENJ. LIYOFILIZE TOZ ICEREN FLAKON, PANTOPRAZOLO EGHydroxyzine
go.drugbank.com/drugs/DB00557ApprovedInvestigationalHydroxyzine is a first-generation histamine H<sub>1</sub>-receptor antagonist of the dephenylmethane and piperazine classes that exhibits sedative, anxiolytic, and antiemetic properties. … [L9677] The active metabolite of hydroxyzine, [cetirizine], is also available as an active ingredient in allergic medications, and is responsible for much of its hydroxyzine's antihistaminic effect.
International brands: Vistaject-50Mixtures: ATARAX FILM TABLET, 30 ADET, ATARAX FILM TABLET, 30 ADETBurosumab
go.drugbank.com/drugs/DB14012ApprovedInvestigationalBurosumab (KRN23) is an entirely human monoclonal IgG1 antibody that binds excess fibroblast growth factor 23 (FGF23) and has been successfully tested in clinical trials in children with X-linked hypophosphatemic … This is the first drug approved to treat adults and children ages 1 year and older with X-linked hypophosphatemia (XLH), which is a rare, inherited form of rickets.
Categories: Fibroblast Growth Factor-23 Blocking AntibodiesProducts: CRYSVITA® SOLUTION FOR INJECTION 10 MG/ML, CRYSVITA 10 MG SOLUTION FOR INJECTIONLevothyroxine
go.drugbank.com/drugs/DB00451ApprovedInvestigationalDesiccated thyroid products contain a ratio of T4 to T3 of 4.2:1, which is significantly lower than the 14:1 ratio of secretion by the human thyroid gland. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.
Mixtures: BITIRON 50 MCG/12.5 MCG TABLET, 100 ADET, SYNTHROID® 112 MCG TABLETASProducts: TİROSİNT 25 MCG/ML ORAL ÇÖZELTİ, 30 ADET, LEVOTIRON 200 MCG TABLET ,100 TABLETGliclazide
go.drugbank.com/drugs/DB01120ApprovedInvestigationalGliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%). … Gliclazide has been shown to decrease fasting plasma glucose, postprandial blood glucose and glycosolated hemoglobin (HbA1c) levels (reflective of the last 8-10 weeks of glucose control).
Mixtures: DUODİA 80 MG/500 MG TABLET, 30 ADET, DUODIA 80/500 MG TABLET, 60 ADETCategories: Drugs Used in Diabetes