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Displaying results 551 - 560 of 10000 in total
  1. Drug

    Febuxostat

    go.drugbank.com/drugs/DB04854
    ApprovedInvestigational

    (CV) fatal outcomes in patients with gout and known cardiovascular disease treated with febuxostat, when compared to those treated with allopurinol. … [A230548] In the following year, the FDA for approved febuxostat for use in the chronic management of hyperuricemia in adult patients with gout who have an inadequate response or intolerance to [allopurinol

    Products: FEBUXOSTAT EG
  2. Target

    Aggrecan core protein

    go.drugbank.com/bio_entities/BE0004104
    TargetHumans

    This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region

    Polypeptides: Aggrecan core proteinSynonyms: Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1
  3. Drug

    Amiodarone

    go.drugbank.com/drugs/DB01118
    ApprovedInvestigational

    [A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.

    Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranProducts: AMIODARONE EG
  4. Drug

    Isotretinoin

    go.drugbank.com/drugs/DB00982
    ApprovedInvestigational

    [L6574] Isotretinoin is associated with major risks in pregnancy and is therefore only available under the iPLEDGE program in the United States. … [L6579] The first isotretinoin-containing product was FDA approved on 7 May 1982.[L6574]

    Categories: Retinoids for Topical Use in AcneProducts: ISOTRETINOINA EG, ISOTRETINOINA DIFA COOPER
  5. Drug

    Phenytoin

    go.drugbank.com/drugs/DB00252
    ApprovedInvestigationalVet approved

    [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications … [A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219]

    Mixtures: GAMIBETAL COMPLEXProducts: Phenytoin ER
  6. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    Zinc oxide is an inorganic compound used in a number of manufacturing processes. … It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fire retardants, and first-aid tapes.

    Mixtures: Medpride En Shield, Esika Pro Instant Perfection 3 En 1 Face Refining Foundation SPF 25 Claro 1 - BeigeCategories: Compounds used in a research, industrial, or household setting
  7. Target

    2-oxoglutarate dehydrogenase complex component E1

    go.drugbank.com/bio_entities/BE0000162
    TargetHumans

    2-oxoglutarate dehydrogenase (E1o) component of the 2-oxoglutarate dehydrogenase complex (OGDHC) (PubMed:24495017, PubMed:25210035, PubMed:28435050). … A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to

    Polypeptides: 2-oxoglutarate dehydrogenase complex component E1
  8. Target

    Cytochrome b6-f complex subunit 4

    go.drugbank.com/bio_entities/BE0002473
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 4Synonyms: Cytochrome b6-f complex subunit IV
  9. Target

    Propionyl-CoA carboxylase complex B subunit

    go.drugbank.com/bio_entities/BE0002846
    TargetStreptomyces coelicolor

    Polypeptides: Propionyl-CoA carboxylase complex B subunit
  10. Target

    Trafficking protein particle complex subunit 3

    go.drugbank.com/bio_entities/BE0003181
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 3