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Telaprevir
go.drugbank.com/drugs/DB05521ApprovedWithdrawnTelaprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotype 1 [FDA Label]. … Approved in May 2011 by the FDA, Incivek was indicated for the treatment of HCV genotype 1 in combination with [DB00811], [DB00008], and [DB00022] [FDA Label].
Nelarabine
go.drugbank.com/drugs/DB01280ApprovedInvestigational[A2332] Due to the rarity of these T-cell malignancies, nelarabine was first granted orphan drug status and a fast-track designation by the FDA to address the unmet therapeutic needs of these cancers. … [A258719] Nelarabine was first granted accelerated approval by the FDA on October 28, 2005, and was manufactured under the trademark name ARRANON by GlaxoSmithKline.
Synonyms: 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purineAmpicillin
go.drugbank.com/drugs/DB00415ApprovedInvestigationalVet approvedAmpicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.
Synonyms: D-(−)-ampicillin, D-(−)-6-(α-aminophenylacetamido)penicillanic acidProducts: AMPICILINA MK TABLETAS DE 250 MG, Nu-ampi Sus 125mg/5mlAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalIn 1996, the FDA approved the use of alprostadil, administered either with an intracavernosal injection or an intraurethral suppository, for the treatment of erectile dysfunction, and it is used in men … This drug causes vasodilation by directly affecting vascular and ductus arteriosus (DA) smooth muscle, preventing or reversing the functional closure of the DA that occurs shortly after birth.
International brands: Kai Tong, Caverject DCIsosorbide mononitrate
go.drugbank.com/drugs/DB01020ApprovedInvestigational[L11698] It is available in oral tablets generically and under the brand name ISMO and Monoket. The extended-release forms of the drug are also available generically and under the brand name Imdur. … [L11743] Isosorbide mononitrate has a longer duration of action than [nitroglycerin] due to its slow onset of absorption and metabolism.
Synonyms: Mononitrato de isosorbidaProducts: ISOSORBIDE MONONITRATO DOC GENERICI, ISOSORBIDE MONONITRATO SIGMA TAU GENERICSAmmonium chloride
go.drugbank.com/drugs/DB06767ApprovedInvestigationalVet approvedAmmonium chloride is an inorganic compound with the formula NH4Cl. It is highly soluble in water producing mildly acidic solutions.
Mixtures: PIM-TRA-KOL PLUS SL (RASA APEL), DM SyrupFlibanserin
go.drugbank.com/drugs/DB04908ApprovedInvestigationalIn February of 2018 Flibanserin was approved by Health Canada under the brand name Addyi for a similar indication as approved by the FDA. … In December of 2025 the FDA expanded the age of the indication to include postmenopausal women, a first for the FDA and sexual health in that age group. [L54893]
Migalastat
go.drugbank.com/drugs/DB05018ApprovedInvestigational[L4274] Migalastat (approved and sold under Amicus Therapeutics' brand name Galafold) is subsequently an oral pharmacological chaperone of alpha-Gal A for the treatment of Fabry disease in adults who … Approval pathway, under which the FDA may approve drugs for serious conditions where there is an unmet medical need and where a drug is shown to have certain effects that are reasonably likely to predict
Isavuconazole
go.drugbank.com/drugs/DB11633ApprovedInvestigationalResistance to isavuconazole has been associated with the mutation in the target gene CYP51 [FDA Label]. … It is proposed that the intravenous and oral dosing can be used interchangeably [L1482], without the need for a repeat loading dose when transitioning from an IV to an oral formulation [A32026].
Brompheniramine
go.drugbank.com/drugs/DB00835ApprovedHistamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
Mixtures: J-tan D Pd, Ru-Hist DProducts: J-tan Pd