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Mavacamten
go.drugbank.com/drugs/DB14921ApprovedInvestigationalMavacamten is a myosin inhibitor indicated for the treatment of adults with symptomatic New York Heart Association (NYHA) class II-III obstructive hypertrophic cardiomyopathy (HCM). … It received initial US FDA approval in 2022, and it is one of the first myosin inhibitors to be used in humans.
Products: CAMZYOS® 2.5MG CAPSULAS DURAS DE LIBERACIÓN INMEDIATA.Memantine
go.drugbank.com/drugs/DB01043ApprovedInvestigationalInitially approved by the FDA in 2013, memantine is an N-methyl-D-aspartate (NMDA) receptor antagonist used in the management of Alzheimer's Disease (AD). … In December 2013, the G8 dementia summit concluded that dementia should be considered a global priority with the objective of developing a cure or a disease-modifying therapy by the year 2025 [L5953, F4366
Mixtures: EUTEBROL-DUOCategories: N-methyl-D-aspartate Receptor AntagonistIndapamide
go.drugbank.com/drugs/DB00808ApprovedInvestigational[A204155] Characterized by an office blood pressure of ≥140/90, hypertension is pervasive and impacts an estimated 25% of adults globally. … [A204155] Thiazide-like diuretics such as indapamide are a valuable tool for the treatment of hypertension and continue to grow in popularity, falling behind only ACE inhibitors in terms of prescription
Mixtures: Ag-perindopril / Indapamide, Ag-perindopril / IndapamideCategories: combinations of sulfonamidesGranisetron
go.drugbank.com/drugs/DB00889ApprovedInvestigationalA serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic and antinauseant for cancer chemotherapy patients.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: GRANI-DENK 1 MG/ ML- AMPOLLA DE 1 ML, Granodex 1mg/ml Solution for Injection or InfusionBicalutamide
go.drugbank.com/drugs/DB01128ApprovedInvestigationalBicalutamide is an oral non-steroidal anti-androgen for prostate cancer. It is comprised of a racemic mixture that is a 50:50 composition of the (R)-bicalutamide and (S)-bicalutamide enantionmers.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: Nu-bicalutamide, Ag-bicalutamideSunflower oil
go.drugbank.com/drugs/DB14329InvestigationalSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: OrgaPlus Super Care Balm for combination and oi ly skin type 20g, OrgaPlus Super Care Balm for combination and oi ly skin type 14gUrea
go.drugbank.com/drugs/DB03904ApprovedInvestigationalA compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
Mixtures: Ti-U-lac Lotion, Ti-U-lac HC LotionProducts: U O CREAM 10%, Kerol ADCetyl ethylhexanoate
go.drugbank.com/drugs/DB11349InvestigationalCetyl ethylhexanoate is an ester of cetyl alcohol and 2-ethylhexanoic acid. It is present in cosmetic products as a skin conditioning agent and emollient.
Products: Sebum Out Finish PactLercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnLercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Mixtures: ENALAPRIL/LERCA AL 10/10MG, ENALAPRIL/LERCA AL 10/10MGProducts: LERCANIDIPIN-HCL AL 10MG, LERCANIDIPIN-HCL AL 20MGFurosemide
go.drugbank.com/drugs/DB00695ApprovedInvestigationalVet approvedFurosemide is a potent loop diuretic that acts on the kidneys to ultimately increase water loss from the body. It is an anthranilic acid derivative. … [A182495] The use of furosemide is particularly beneficial in clinical settings that require a drug with a higher diuretic potential.
Mixtures: SPIRO D TABLINEN 100MGCategories: Increased Diuresis at Loop of Henle, combinations of sulfonamides