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Ioxaglic acid
go.drugbank.com/drugs/DB09313ApprovedWithdrawnThis drug is an ionic tri-iodinated benzoate used as a low-osmolality contrast agent during diagnostic imaging procedures. … Like other organic iodine compounds, ioxaglic acid blocks x-rays and is opaque in its appearance on x-ray film, improving the visualization of important structures and organs during angiography, arteriography
Categories: Compounds used in a research, industrial, or household setting, X-Ray Contrast ActivityProducts: HEXABRIX 320 INJECTION 320 mgI/mlFosamprenavir
go.drugbank.com/drugs/DB01319ApprovedInvestigationalFosamprenavir is a prodrug of amprenavir, an inhibitor of human immunodeficiency virus (HIV) protease.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 SubstratesProducts: TELZIR®, TELZIR 700 MG FİLM KAPLI TABLET, 60 ADETAcipimox
go.drugbank.com/drugs/DB09055ApprovedInvestigationalAcipimox is a niacin derivative used as a hypolipidemic agent. … Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.
Categories: Heterocyclic Compounds, 1-RingProducts: OLBETAM CAPSULE 250 mgImidapril
go.drugbank.com/drugs/DB11783InvestigationalImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
Categories: Heterocyclic Compounds, 1-Ring, Agents Acting on the Renin-Angiotensin SystemProducts: TANATRIL TABLETS 5 mg, TANATRIL TABLETS 10 mgVorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalIt is the first in a new class of agents known as histone deacetylase inhibitors. … A recent study suggested that vorinostat also possesses some activity against recurrent glioblastoma multiforme, resulting in a median overall survival of 5.7 months (compared to 4 - 4.4 months in earlier
Products: ZOLINZA®VORINOSTAT 100 MG CAPSULASMetyrapone
go.drugbank.com/drugs/DB01011ApprovedInvestigationalAn inhibitor of the enzyme steroid 11-beta-monooxygenase. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of cushing syndrome.
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2A6 InhibitorsProducts: Metycor 250 mg WeichkapselnPentostatin
go.drugbank.com/drugs/DB00552ApprovedInvestigationalA potent inhibitor of adenosine deaminase. The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia. … It is also synergistic with some other antineoplastic agents and has immunosuppressive activity.
Categories: Heterocyclic Compounds, 1-Ring, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: CIPROFLOXACINO TABLETAS RECUBIERTAS 500 MG.Centella asiatica
go.drugbank.com/drugs/DB14256ApprovedCentella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Mixtures: MADECASSOL C, Centella 65 Green Tea PackSynonyms: Ma Ti Cao Whole, Luo De Da WholeGamma-aminobutyric acid receptor subunit alpha-5
go.drugbank.com/bio_entities/BE0000471TargetHumansExtrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … GABAARs containing alpha-5/GABRA5 subunits are mainly extrasynaptic and contribute to the tonic GABAergic inhibition in the hippocampus (By similarity).
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABAAR subunit alpha-5, GABA(A) receptor subunit alpha-5Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
go.drugbank.com/bio_entities/BE0002192TargetHumansForms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links
Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2