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Displaying results 5601 - 5610 of 10000 in total
  1. Drug

    Telcagepant

    go.drugbank.com/drugs/DB12228
    Investigational

    It is an antagonist of the receptor for calcitonin gene-related peptide (CGRP), a primary neuropeptide involved in the pathophysiology of migraine. … CGRP and its receptors are found in areas of the central and peripheral nervous system that are important for the transmission of migraine pain.

  2. Drug

    JB991

    go.drugbank.com/drugs/DB05081
    Experimental

    In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug will be applied topically on the skin. … The drug exerts marked antiproliferative and pro-apoptotic effect in human keratinocytes and fibroblasts in vitro.

  3. Drug

    Sovleplenib

    go.drugbank.com/drugs/DB17557
    Investigational

    It is under investigation in clinical trial NCT03483948 (Phase I Study of Hmpl-523+azacitidine in Elderly Patients With Acute Myeloid Leukemia).

  4. Drug

    Metampicillin

    go.drugbank.com/drugs/DB13836
    Experimental

    It is hydrolysed in aqueous solution to form ampicillin. Hydrolysis is rapid under acid conditions like the stomach.

  5. Drug

    Technetium Tc-99m

    go.drugbank.com/drugs/DB14227
    Investigational

    It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

  6. Drug

    tgAAVCF

    go.drugbank.com/drugs/DB17849
    Investigational

    It is being investigated for the treatment of cystic fibrosis.[A259821, A259826] … tgAAVCF is an adeno-associated virus (AAV) vector encoding the human cystic fibrosis transmembrane conductance regulator protein (CFTR) cDNA.

  7. Drug

    Gold

    go.drugbank.com/drugs/DB14154
    Investigational

    It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts.

  8. Drug

    Ditekiren

    go.drugbank.com/drugs/DB19992
    Experimental

    The usage of the INN stem '-kiren' in the name indicates that Ditekiren is a renin inhibitor. Ditekiren has a monoisotopic molecular weight of 929.57 Da.

    Categories: Agents Acting on the Renin-Angiotensin System
  9. Drug

    Gusperimus

    go.drugbank.com/drugs/DB12692
    Investigational

    Gusperimus has been used in trials studying the treatment of Lupus Nephritis, Wegeners Granulomatosis, and Wegener's Granulomatosis.

    Categories: Compounds used in a research, industrial, or household setting
  10. Drug

    ATL1101

    go.drugbank.com/drugs/DB05023
    Experimental

    ATL1101 is a second-generation antisense drug designed to block the synthesis of the IGF-1 receptor, a protein involved in the regulation of cell overgrowth in psoriasis.