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Oral Polio Vaccine
go.drugbank.com/drugs/DB15864InvestigationalAfter administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population[A220163] … The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes.
Lemzoparlimab
go.drugbank.com/drugs/DB17572InvestigationalIV and Venetoclax Orally in Participants With Acute Myeloid Leukemia and With Azacitidine With or Without Venetoclax in Participants With Myelodysplastic Syndrome). … Lemzoparlimab is under investigation in clinical trial NCT04912063 (Study to Evaluate Adverse Events and Movement of Lemzoparlimab in Body When Used Intravenously (IV) With Azacitidine Subcutaneously or
Tifcemalimab
go.drugbank.com/drugs/DB18914InvestigationalLung Cancer (LS-SCLC)). … Tifcemalimab is under investigation in clinical trial NCT06095583 (Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell
Diazepinomicin
go.drugbank.com/drugs/DB12420InvestigationalDiazepinomicin is a natural product derived from a non-pathogenic micro-organism. … It is a proprietary first-in-class small molecule with the potential to treat multiple solid tumours like the well known chemotherapeutics, doxorubicin and mitomycin C.
Synonyms: 4,6,8-trihydroxy-10-(3,7,11-trimethyldodeca-2,6,10-trienyl)-5,10-dihydrodibenzo(b,e)(1,4)diazepin-11-oneVanoxerine
go.drugbank.com/drugs/DB03701InvestigationalVanoxerine is a highly selective dopamine transporter antagonist. It was synthesized in the late 1970s and developed as a potential treatment for depression. … [A248555] Vanoxerine is an investigational drug and has not been approved for therapeutic use.
PXS-4728A free base
go.drugbank.com/drugs/DB19177InvestigationalPXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder).
Synonyms: Benzamide, 4-(((2e)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-n-(1,1-dimethylethyl)-Tandamine
go.drugbank.com/drugs/DB09192ExperimentalTandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
Zotarolimus
go.drugbank.com/drugs/DB18761InvestigationalZotarolimus is an immunosuppressant under investigation for use in drug-eluting stents.
Temocillin
go.drugbank.com/drugs/DB12343ApprovedInvestigationalWithdrawnTemocillin has been investigated in Infection, Liver Dysfunction, and Urinary Tract Infection.
FP-1096
go.drugbank.com/drugs/DB05310ExperimentalFP1096 reduced the painful symptoms of endometriosis in trial subjects with very minimal side effect.