PXS-4728A free base

DB19177InvestigationalSmall molecule

PXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder).

Chemical structure of PXS-4728A free base
Formula / weight
C15H21FN2O2 · 280.343 g/mol (avg)
Also known as
Benzamide, 4-(((2e)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-n-(1,1-dimethylethyl)-
Code names
BI-1467335 free base · PXS-4728

Resolves to

Structure
InChIKeyOWNSXNXYELKDSO-DHZHZOJOSA-NSMILESCC(C)(C)NC(=O)C1=CC=C(OC\C(CN)=C\F)C=C1
Targets

What you can answer from here — as of September 05, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1Clinical trialPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with PXS-4728A free base, and which of those have an active Phase 3 trial?

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