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Rheinanthrone
go.drugbank.com/drugs/DB13175ExperimentalRheinanthrone is the active metabolite of senna glycoside [DB11365] known for its laxative effect [A19235]. It is commonly produced by plants of the Rheum species [L772].
Nelotanserin
go.drugbank.com/drugs/DB12555InvestigationalIt is a highly selective antagonist at the 5-HT2A serotonin receptor. It increases non-REM sleep, the most restorative phase of the sleep cycle, without sacrificing REM or dream sleep. … Nelotanserin has been used in trials studying the treatment of Lewy Body Dementia, Visual Hallucinations, Dementia With Lewy Bodies, and REM Sleep Behavior Disorder.
CHO Cells Recombinant Vaccine
go.drugbank.com/drugs/DB15893ExperimentalThe vaccine candidate is sponsored by Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. and is undergoing phase I clinical trials to evaluate safety and tolerability.
PPI-1019
go.drugbank.com/drugs/DB05832InvestigationalApan (PPI-1019) is developed by Praecis Pharmaceuticals to treat Alzheimer's Disease.
Iroxanadine
go.drugbank.com/drugs/DB05444ExperimentalBRX-235 also causes translocation of calcium-dependent protein kinase C isoform to membranes.
Interleukin-7
go.drugbank.com/drugs/DB11997InvestigationalInterleukin 7 has been used in trials studying the treatment of Metastatic Breast Cancer.
Platelet Lysate
go.drugbank.com/drugs/DB15869InvestigationalPlatelet lysate is an acellular compound composed of platelet proteins while also being void of cellular debris, thus making the lysate rich with growth factors. … [A220188] It is extracted through lysis of the plasma membrane of platelets. Because white cell antigens are low in prepared lysate, there is a minimized likelihood of immune responses.
BGB-DXP593
go.drugbank.com/drugs/DB16357InvestigationalWith Mild-to-Moderate Coronavirus Disease 2019 (COVID-19)) by BeiGene. … [L27401] It is currently being investigated against COVID-19 in the clinical trial NCT04551898 (Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Neutralizing Antibody BGB-DXP593 in Participants
AZD2389
go.drugbank.com/drugs/DB22104InvestigationalNCT06973005: A Study to Investigate How Multiple Oral Doses of AZD2389 Affect the Pharmacokinetics of Midazolam, Caffeine, and Bupropion in Healthy Participants).
Nicotinamide adenine dinucleotide phosphate
go.drugbank.com/drugs/DB03461ExperimentalA coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate.