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Displaying results 5671 - 5680 of 10000 in total
  1. Drug

    Amlodipine

    go.drugbank.com/drugs/DB00381
    ApprovedInvestigational

    Due to their selectivity for the peripheral blood vessels, dihydropyridine calcium channel blockers are associated with a lower incidence of myocardial depression and cardiac conduction abnormalities than … Amlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called _dihydropyridine calcium channel blockers_.

    Synonyms: (RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate, 3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylateInternational brands: Atecard-AM, Amlodipine 5
  2. Drug

    Lipoic acid

    go.drugbank.com/drugs/DB00166
    ApprovedInvestigationalNutraceutical

    A vitamin-like antioxidant.

    Synonyms: D-thioctic acid, Thioctic acid D-formMixtures: VitaHealth L-Glutathione Plus, Protect Cardio AF
  3. Drug

    Hydrogenated soybean lecithin

    go.drugbank.com/drugs/DB14157
    Investigational

    Synonyms: Soya lecithin, hydrogenated, Soya lecithins, hydrogenated
  4. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.

    Synonyms: L-Hyoscyamine, L-Tropine tropateMixtures: Uro-L, Urin D/S
  5. Drug

    Domiphen

    go.drugbank.com/drugs/DB11594
    Approved

    Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.

    Synonyms: 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl), Dodecyldimethyl(2-phenoxyethyl)ammoniumProducts: Ora-septic Cerises Loz 1.5mg
  6. Drug

    Ranitidine

    go.drugbank.com/drugs/DB00863
    ApprovedWithdrawn

    Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as [cimetidine] and [famotidine]. … [A176843] Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related

    Categories: MATE 1 Inhibitors, MATE 2 InhibitorsProducts: SAMPEP TABLETAS DE 150 MG, RANITIDIN AL 150
  7. Indication

    Ankle spasticity following a stroke or traumatic brain injury

    go.drugbank.com/conditions/DBCOND0133858
    Drugs: Clostridium botulinum
    Synonyms: Ankle spasticity following a stroke or traumatic brain injury
  8. Target

    3-hydroxy-3-methylglutaryl-coenzyme A reductase

    go.drugbank.com/bio_entities/BE0000574
    TargetEnzymeHumans

    HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular

    Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A binding
  9. Target

    Acetyl-coenzyme A synthetase 2-like, mitochondrial

    go.drugbank.com/bio_entities/BE0000746
    TargetHumans

    Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity) … Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).

    Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrial
  10. Target

    2-amino-3-ketobutyrate coenzyme A ligase

    go.drugbank.com/bio_entities/BE0002049
    TargetEscherichia coli (strain K12)

    Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.

    Polypeptides: 2-amino-3-ketobutyrate coenzyme A ligase