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Donanemab
go.drugbank.com/drugs/DB16647ApprovedInvestigational[A232214] On July 2, 2024, donanemab was approved by the FDA for the treatment of AD in patients with mild cognitive impairment or dementia symptoms.
ACR-16
go.drugbank.com/drugs/DB05371InvestigationalACR-16 is under investigation by NeuroSearch. ACR16 has been successfully investigated in a Phase II multi-centre, randomised and placebo-controlled trial in patients with Huntington’s disease as well as in three Phase Ib studies within ...
Strontium chloride Sr-89
go.drugbank.com/drugs/DB09498ApprovedStrontium chloride (Sr-89), initially FDA-approved in 1993, is used as a paliative therapeutic option to help relieve the pain from bone metastases. Strontium chloride is mainly used in cases of metastatic castrate-resistant prostate can...
Oxomemazine
go.drugbank.com/drugs/DB13820InvestigationalOxomemazine is a phenothiazine derivative.
Categories: Antihistamines for Systemic UsePractolol
go.drugbank.com/drugs/DB01297ApprovedA beta-adrenergic antagonist that has been used in the emergency treatment of cardiac arrhythmias.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesOxaprotiline
go.drugbank.com/drugs/DB09307ExperimentalBoth enantiomers have antidepressant effects but levoprotiline also is an antihistamine and dextroprotiline has many other pharmacological actions.
OTL-201
go.drugbank.com/drugs/DB17652ExperimentalOTL-201 is an investigational hematopoietic stem cell (HSC) gene therapy being developed by Orchard Therapeutics for the treatment of mucopolysaccharidosis type IIIA (MPS-IIIA).
Octacosanol
go.drugbank.com/drugs/DB11220InvestigationalNutraceuticalThis high–molecular-weight organic compound is the main component of a natural product wax extracted from plants [A27245]. 1-octacosanol is reported to possess cholesterol-lowering effects, antiaggregatory … It has been studied as a potential therapeutic agent for the treatment of Parkinson's disease.
Benzoylecgonine
go.drugbank.com/drugs/DB01515ExperimentalIllicitIt is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States.