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Ambroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalSurfactants acts as an anti-glue factor by reducing the adhesion of mucus to the bronchial wall, in improving its transport and in providing protection against infection and irritating agents. … The substance is a mucoactive drug with several properties including secretolytic and secretomotoric actions that restore the physiological clearance mechanisms of the respiratory tract which play an important
Mixtures: EBROMIN-P, AXOL DUOCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesDihydro-alpha-ergocryptine
go.drugbank.com/drugs/DB11274ApprovedThis structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine.[T195] Both compounds are hydrogenated ergot derivatives. … Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. To know more about this mixture, please visit [DB01049]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesBeta carotene
go.drugbank.com/drugs/DB06755ApprovedNutraceuticalIt is an antioxidant that can be found in yellow, orange and green leafy vegetables and fruits.[T158] Under the FDA, beta-carotene is considered as a generally recognized as safe substance (GRAS).
Mixtures: Escavite D, Triveen-Duo DHAProducts: Betacarotene 25000 Iu, Betacarotene 10000 IuCimetidine
go.drugbank.com/drugs/DB00501ApprovedInvestigationalIt also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy.
Categories: P-glycoprotein inducers, P-glycoprotein substratesProducts: DG Health Heartburn Relief, Nu-cimet Tab 600mgPhenylalanine
go.drugbank.com/drugs/DB00120ApprovedInvestigationalNutraceuticalPhenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].
Mixtures: SOLUCION DP-AMINE, TRAVASOL PLUS 15% LIBRE DE BISULFITOBrexpiprazole
go.drugbank.com/drugs/DB09128ApprovedInvestigationalBrexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM). … Compared to aripiprazole, brexpiprazole has less potential for partial agonist-mediated adverse effects such as extrapyramidal symptoms, which is attributed to lower intrinsic activity at the D2 receptor
Categories: Dopamine D2 Receptor Agonists, Cytochrome P-450 SubstratesSynonyms: Lu-AF41156Phosphatidyl serine
go.drugbank.com/drugs/DB00144ApprovedNutraceuticalPS has been shown to slow cognitive decline in animal models. … Because of the potentail cognitive benefits of phosphatidylserine, the substance is sold as a dietary supplement to people who believe they can benefit from an increased intake.
Synonyms: PSInternational brands: LifeExtension PS CapsBetaine
go.drugbank.com/drugs/DB06756ApprovedInvestigationalNutraceutical[A252235,A252240] Homocystinuria is an inherited disorder that leads to the accumulation of homocysteine in plasma and urine. … However, in order to normalize homocysteine levels, patients can be treated with vitamin B6 ([pyridoxine]), vitamin B12 ([cobalamin]), [folate] and specific diets.
Mixtures: Alka-pan Tablets, Face It Hd Perfect Bb Spf30 Pa 02Certolizumab pegol
go.drugbank.com/drugs/DB08904ApprovedInvestigational[A176585] It is formed with a humanized Fab fragment of 50 kDa, from an IgG 1 isotype, fused to a 40 kDa polyethylene glycol moiety replacing the Fc antibody region. … [A176606] Certolizumab does not require glycosylation for active function and hence, its production is significantly more affordable when compared to other existing TNF-alpha therapies as it can be
Mifamurtide
go.drugbank.com/drugs/DB13615ApprovedInvestigationalAlso called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). … Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes.