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Displaying results 561 - 570 of 8695 in total
  1. Drug

    Spesolimab

    go.drugbank.com/drugs/DB15626
    ApprovedInvestigational

    Spesolimab is an interleukin-36 (IL-36) receptor antagonist. … [A252220, A252225] Spesolimab received recommendations from the EMA's Committee for Medicinal Products for Human Use (CHMP) to be granted marketing authorization in October 2022 and was finally approved

    Categories: Interleukin-36 Receptor AntagonistSynonyms: Immunoglobulin G1, anti-(human interleukin 36 receptor) (humanized monoclonal BI 655130 gamma1-chain), disulfide with humanized monoclonal BI 655130 kappa-chain, dimer
  2. Drug

    Glycopyrronium

    go.drugbank.com/drugs/DB00986
    ApprovedInvestigationalVet approved

    [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers. … [L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium].

    Categories: Drugs for Obstructive Airway Diseases, Drugs for Functional Gastrointestinal DisordersProducts: Glyrx-PF, GLYCO-P
  3. Drug

    Acetylcysteine

    go.drugbank.com/drugs/DB06151
    ApprovedInvestigational

    Acetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.

    Mixtures: N-ACETILCISTEÍNA MAS GUAYACOLATO DE GLICERILO, Trimix isokal Emulsion zur InfusionCategories: Antidote for Acetaminophen Overdose
  4. Drug

    Ensovibep

    go.drugbank.com/drugs/DB19078
    Investigational

    Ensovibep is under investigation in clinical trial NCT04501978 (ACTIV-3: Therapeutics for Inpatients With COVID-19).

    Synonyms: glycoprotein receptor binding domain-binding), Designed ankyrin repeat protein (synthetic bivalent human albumin-binding) fusion protein with designed ankyrin repeat protein (synthetic trivalent severe acute respiratory syndrome coronavirus 2 spike
  5. Drug

    Lanreotide

    go.drugbank.com/drugs/DB06791
    ApprovedInvestigational

    Lanreotide was first approved for use in the United States by the FDA on August 30, 2007.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg, Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mg
  6. Drug

    Plantago ovata seed

    go.drugbank.com/drugs/DB14585
    ApprovedWithdrawn

    Categories: Drugs for ConstipationProducts: EVAGEL POWDER FOR ORAL SOLUTION 3.5g, CONSIGEL POWDER FOR ORAL SOLUTION 3.5G
  7. Drug

    Basiliximab

    go.drugbank.com/drugs/DB00074
    ApprovedInvestigational

    A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also … It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cell line genetically engineered to express plasmids containing the human heavy and light chain constant region genes

    Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT FOR INJECTION 20 mg/vial, SIMULECT LYOPHILISATE FOR INJECTION 20MG PER VIAL
  8. Drug

    Chorionic Gonadotropin (Human)

    go.drugbank.com/drugs/DB09126
    ApprovedInvestigationalVet approved

    HCG is composed of an alpha and a beta sub-unit. … This allows the corpus luteum to continuously secrete the hormone progesterone during the first trimester, which is required for maintenance of the uterus and prevents menstruation.

    Products: . - Pulver und Lösungsmittel zur Herstellung einer Injektionslösung, Powder and Solvent for Solution for Injection
  9. Drug

    Cyanocobalamin

    go.drugbank.com/drugs/DB00115
    ApprovedInvestigationalNutraceutical

    Vitamin B12 has many forms, including the cyano-, methyl-, deoxyadenosyl- and hydroxy-cobalamin forms. … This vitamin is produced naturally by bacteria [A175276], and is necessary for DNA synthesis and cellular energy production.

    Mixtures: For Men, Prenate MaxProducts: Rubramin PC
  10. Drug

    Calfactant

    go.drugbank.com/drugs/DB06415
    ApprovedInvestigational

    It is an off-white suspension of an extract of natural surfactant from calf lungs suspended in 0.9% saline. … Calfactant is a sterile, non-pyrogenic lung surfactant intended for intratracheal instillation.

    Products: BLES (bovine lipid extract surfactant) 27 mg/ml Suspension for Intratracheal Instillation