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Displaying results 561 - 570 of 10000 in total
  1. Drug

    Atibuclimab

    go.drugbank.com/drugs/DB06546
    Investigational

    Atibuclimab (IC14) is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis.

    Synonyms: IC14, (RECOMBINANT CHIMERIC MAB AGAINST HUMAN CD14), IMMUNOGLOBULIN G4, ANTI-(HUMAN CD14 ANTIGEN) (HUMAN-MUS MUSCULUS MONOCLONAL IC14 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL IC14 .KAPPA.-CHAIN, DIMER
  2. Drug

    Ambrisentan

    go.drugbank.com/drugs/DB06403
    ApprovedInvestigational

    Ambrisentan is an orally active selective type A endothelin receptor antagonist indicated for the treatment of pulmonary arterial hypertension. … As an endothelin receptor antagonist, Ambrisentan prevents endogenous endothelin peptide from constricting the muscles in blood vessels, allowing them to relax and permit a reduction in blood pressure.

    Synonyms: (2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acidCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  3. Drug

    Tucatinib

    go.drugbank.com/drugs/DB11652
    ApprovedInvestigational

    Tucatinib is a kinase inhibitor drug used with [trastuzumab] and [capecitabine] in the treatment of unresectable or metastatic HER-2 positive breast cancer. … [L12951] Tucatinib is a promising new treatment for patients with metastatic breast cancer who have not responded adequately to other chemotherapy regimens.[L12945]

    Categories: MATE 1 Inhibitors, MATE 2 Inhibitors
  4. Drug

    Xylose

    go.drugbank.com/drugs/DB09419
    ApprovedWithdrawn

    Nevertheless, xylose by itself may not necessarily serve many purposes immediately - but its metabolism results in a variety of substrates that can serve important nutritional and biological purposes. … Xylose is a monosaccharide of the aldopentose type consisted of five carbon atoms and an aldehyde functional group. Xylose is a sugar isolated from wood.

    Synonyms: D-Xylose, aldehydo-D-xylose
  5. Drug

    Calcium

    go.drugbank.com/drugs/DB01373
    ApprovedInvestigationalNutraceutical

    Low calcium intake may also be a risk factor in the development of osteoporosis. The best-absorbed form of calcium from a pill is a calcium salt like carbonate or phosphate. … Although calcium flow to and from the bone is neutral, about 5 mmol is turned over a day. Bone serves as an important storage point for calcium, as it contains 99% of the total body calcium.

    Mixtures: Supplements De Vitamines Et Mineraux, Cal/mag+dCategories: ascorbic acid (vit C) and calcium
  6. Drug

    Avobenzone

    go.drugbank.com/drugs/DB09495
    ApprovedInvestigational

    Avobenzone has an absorption maximum of 357 nm. Sunscreens containing avobenzone is indicated for providing protection from the sun. … It is included in many commercially available sunscreens which are used as wide spectrum sunscreens.

    Mixtures: Mia Del Mar SPF 30 Moisturizer, Every Man Jack SPF 30 SunscreenCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  7. Drug

    Exebacase

    go.drugbank.com/drugs/DB16161
    Investigational

    Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia).

    Synonyms: Des-met1-putative phage lysin (streptococcus phage phi891591), produced in escherichia coli
  8. Drug

    Technetium Tc-99m etifenin

    go.drugbank.com/drugs/DB13183
    Investigational

    Products: EHIDA KIT PARA LA PREPARACIÓN DE RADIOFÁRMACOS.
  9. Drug

    Recifercept

    go.drugbank.com/drugs/DB17899
    Investigational

    Synonyms: Human fibroblast growth factor receptor 3 (fgfr-3, cd333) (1-336)-(401-413) fragment (1-349) (soluble isoform (337-400>del, 414-784>del)-sfgfr3), produced in chinese hamster ovary (cho) cells, glycoform, Recombinant human fibroblast growth factor receptor 3
  10. Drug

    WIN 55212-2

    go.drugbank.com/drugs/DB13950
    Experimental

    WIN 55,212-2 is a chemical described as an aminoalkylindole derivative, which produces effects similar to those of cannabinoids such as tetrahydrocannabinol (THC) but has an entirely different chemical … It is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling.

    Synonyms: (2,3-Dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl)methanone monomethanesulfonateSalts: WIN 55212-2 mesylate