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Displaying results 561 - 570 of 10000 in total
  1. Indication

    Homozygous for F508del mutation in the CFTR gene

    go.drugbank.com/conditions/DBCOND0102747
    Drugs: Ivacaftor
    Synonyms: Homozygous for F508del mutation in the CFTR gene
  2. Drug

    Amikacin

    go.drugbank.com/drugs/DB00479
    ApprovedInvestigationalVet approved

    [F1949] In September 2018, a liposomal inhalation suspension of this drug was approved by the FDA for the treatment of lung disease caused by Mycobacterium avium complex (MAC) bacteria in a small population … of patients with the disease who do not respond to traditional treatment.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseSynonyms: 1-N-(L(−)-γ-amino-α-hydroxybutyryl)kanamycin A, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->4)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL-(1->6))-N(SUP 3)-(4-AMINO-L-2-HYDROXYBUTYRYL)-2-DEOXY-L-STREPTAMINE
  3. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids. … It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: . - Salbe + Nagelset, Thomas Formula No 17Products: BASODEXAN 100MG/G SALBE, UO CREAM
  4. Drug

    Loratadine

    go.drugbank.com/drugs/DB00455
    ApprovedInvestigational

    Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis. … [A176435] A lack of sedative and CNS adverse effects make loratadine, along with other second generation antihistamines, preferable over their 1st generation counterparts in many clinical situations.

    Mixtures: THERAFLU N 12, DESENFRIOL-ON GRAGEAS REPETABSCategories: Antihistamines for Systemic Use, Histamine H1 Antagonists, Non-Sedating
  5. Drug

    Daratumumab

    go.drugbank.com/drugs/DB09331
    ApprovedInvestigational

    [L13290] It is approved for the treatment of multiple myeloma as monotherapy or combination therapy and light chain (AL) amyloidosis in combination with other drugs. … In July 2024, it was further approved in combination with bortezomib, lenalidomide, and dexamethasone (D-VRd) for induction and consolidation therapy in newly diagnosed, transplant-eligible patients.

    Products: Darzalex IV, DARZALEX CONCENTRATE FOR SOLUTION FOR INFUSION 400MG/20ML
  6. Drug

    Hydralazine

    go.drugbank.com/drugs/DB01275
    ApprovedInvestigational

    [A186820,L8782,L8785] Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications. … [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.

    Categories: Arteriolar Smooth Muscle, Agents Acting On, Antihypertensive Agents Indicated for HypertensionProducts: APRESOLINE FOR INJECTION 20 mg/ampoule, Nu-hydral Tab 10mg
  7. Drug

    Ifosfamide

    go.drugbank.com/drugs/DB01181
    ApprovedInvestigational

    Ifosfamide is a chemotherapeutic agent chemically related to the nitrogen mustards and a synthetic analog of cyclophosphamide. It is active as an alkylating agent and an immunosuppressive agent.

    Products: IFO-cell N 1000; Solution for Infusion (1000mg per vial), IFO-CELL N 1000
  8. Drug

    Yeast

    go.drugbank.com/drugs/DB11017
    Approved

    Yeast allergenic extract is used in allergenic testing.

    Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Fungal Allergenic ExtractProducts: REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 10 ADET, REFLOR 250 MG LIYOFILIZE TOZ ICEREN SASE, 20 ADET
  9. Drug

    Mitomycin

    go.drugbank.com/drugs/DB00305
    ApprovedInvestigational

    [A193419] Mitomycin's cross-linking activity has resulted in its approval for the treatment of a variety of cancers - the most recent of which is an April 2020 approval for its use in low-grade Upper … Mitomycin is an antineoplastic antibiotic first isolated by Japanese microbiologists in the 1950s from cultures of _Streptomyces caespitosus_.

    Synonyms: Mitomycin-XCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Spectinomycin

    go.drugbank.com/drugs/DB00919
    ApprovedVet approvedWithdrawn

    An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of gonorrhea.

    Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: TROBICIN FOR INJECTION 2 g/vial, Trobicin Inj 400mg/ml