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Acyclovir
go.drugbank.com/drugs/DB00787ApprovedInvestigationalAcyclovir is a deoxynucleoside analog antiviral used to treat herpes simplex, Varicella zoster, herpes zoster, herpes labialis, and acute herpetic keratitis. Acyclovir is generally used first line in the treatment of these viruses and so...
Products: Zovirax Cap 200mg, AVIREX-UMagnesium sulfate
go.drugbank.com/drugs/DB00653ApprovedInvestigationalVet approvedA small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia.
Mixtures: Tis-U-Sol, Tis-U-solViloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnIt was first approved in the UK in 1974; however, the immediate-release formulation was discontinued due to business reasons unrelated to drug safety and efficacy. … In April 2021, an extended-release formulation of viloxazine under the brand name QELBREE was approved by the FDA for the treatment of attention deficit hyperactivity disorder (ADHD).[A247985]
Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[L32813] Vildagliptin is currently under investigation in the US. … Vildagliptin (LAF237) is an orally active antihyperglycemic agent that selectively inhibits the dipeptidyl peptidase-4 (DPP-4) enzyme.
Mixtures: GALVUS® MET 50/500 COMPRIMIDOS RECUBIERTOS CON PELICULA, GALVUS® MET COMPRIMIDO RECUBIERTO CON PELICULA 50 MG/850 MGCalcium chloride
go.drugbank.com/drugs/DB01164ApprovedInvestigationalIt can be produced directly from limestone, but large amounts are also produced as a by-product of the Solvay process. Because of its hygroscopic nature, it must be kept in tightly-sealed containers. … Calcium chloride is an ionic compound of calcium and chlorine. It is highly soluble in water and it is deliquescent.
Mixtures: K+36.8, Delflex Perit.dial.soL.1.5%dex.low Ca Low mgVitamin D
go.drugbank.com/drugs/DB11094ApprovedInvestigationalNutraceuticalVet approvedSince vitamin D can be endogenously synthesized in adequate amounts by most mammals exposed to sufficient quantities of sunlight, vitamin D functions like a hormone on vitamin D receptors to regulate calcium … Vitamin D plays an essential physiological role in maintaining calcium homeostasis and metabolism.
Mixtures: Ch-P Cap, Cal/mag+dAzithromycin
go.drugbank.com/drugs/DB00207ApprovedInvestigationalIt was initially approved by the FDA in 1991 [A174175]. … In March 2020, a small study was funded by the French government to investigate the treatment of COVID-19 with a combination of azithromycin and the anti-malaria drug [hydroxychloroquine].
Products: Zithromax Cap 250mg, ZITHROMAX TR-SAFT K B 25KGOxamniquine
go.drugbank.com/drugs/DB01096ApprovedOxamniquine causes worms to shift from the mesenteric veins to the liver where the male worms are retained; the female worms return to the mesentery, but can no longer release eggs. … An anthelmintic with schistosomicidal activity against Schistosoma mansoni, but not against other Schistosoma spp.
Prasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalIn Canada, a prescription is required to buy DHEA. … Dehydroepiandrosterone (DHEA) can be converted to testosterone; androstenedione; estradiol; and estrone. Most of DHEA is sulfated (dehydroepiandrosterone sulfate) before secretion.
Carglumic acid
go.drugbank.com/drugs/DB06775ApprovedInvestigationalThis rare genetic disorder results in elevated blood levels of ammonia, which can eventually cross the blood–brain barrier and cause neurologic problems, cerebral edema, coma, and death. … Carglumic acid was approved by the U.S. Food and Drug Administration (FDA) on 18 March 2010.