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AK119
go.drugbank.com/drugs/DB16423InvestigationalAK119 is a humanized anti-CD73 monoclonal antibody being investigated in the clinical trial NCT04516564 (A Study of AK119 (Anti-CD73 Antibody), a Treatment for COVID-19, in Healthy Subjects).[L28315]
Bifunctional epoxide hydrolase 2
go.drugbank.com/drugs/DB15139InvestigationalBifunctional epoxide hydrolase 2 is under investigation in clinical trial NCT00654966 (Evaluation of the Effects of Urotensin-II and Soluble Epoxide Hydrolase Inhibitors on Skin Microvessel Tone in Patients … With Heart Failure, and in Healthy Volunteers).
Protionamide
go.drugbank.com/drugs/DB12667ApprovedInvestigationalWithdrawnProthionamide has been used in trials studying the treatment of MDR-TB and HIV Infections.
Trenonacog alfa
go.drugbank.com/drugs/DB13201InvestigationalHuman coagulation factor IX (EC 3.4.21.22, Christmas factor, plasma thromboplastin component), produced in CHO cells.
Danofloxacin
go.drugbank.com/drugs/DB11393ExperimentalVet approvedDanofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Etesevimab
go.drugbank.com/drugs/DB15897Investigational[L16651,L16661] Under the EUA granted in February 2021, etesevimab is used in combination with [bamlanivimab] to treat mild to moderate COVID-19 in adults and pediatric patients who are at high risk for … [L40174] The EUA currently allows bamlanivimab and etesevimab for post-exposure prophylaxis of COVID-19 in adults and children.[L40179]
DLO6002
go.drugbank.com/drugs/DB05179ExperimentalDLO6002 is developed by Summit Corporation and is in phase I of clinical trials for the treatment of Parkinson's disease.
Isothipendyl
go.drugbank.com/drugs/DB08802InvestigationalIsothipendyl is an antihistamine and anticholinergic used as an antipruritic.
PXS-4728A free base
go.drugbank.com/drugs/DB19177InvestigationalPXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder).
Synonyms: Benzamide, 4-(((2e)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-n-(1,1-dimethylethyl)-Tandamine
go.drugbank.com/drugs/DB09192ExperimentalTandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).