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KD7040
go.drugbank.com/drugs/DB05214InvestigationalIt is being developed by Kalypsys. … KD7040 is a topically-delivered inducible nitric oxide synthase (iNOS) inhibitor for the treatment of neuropathic pain. The KD7040 IND was filed in 4Q06, and a Phase Ib clinical trial began 2Q07.
REN-850
go.drugbank.com/drugs/DB05912ExperimentalREN-850 is an oral drug for multiple sclerosis which is in Phase I of clinical trials.
Sovateltide
go.drugbank.com/drugs/DB06138InvestigationalIn animal models SPI-1620 selectively and transiently increases tumor blood flow allowing increased delivery of anticancer agents to the tumor. It is being developed as an adjunct to chemotherapy.
BIIB015
go.drugbank.com/drugs/DB06304InvestigationalIt has been investigated for the treatment of subjects with relapsed or refractory solid tumours.
TW-37
go.drugbank.com/drugs/DB17059ExperimentalTW-37 is a small-molecule inhibitor of Bcl-2 investigated for its anti-cancer properties.[A253157]
Crenolanib
go.drugbank.com/drugs/DB11832InvestigationalCrenolanib is under investigation for the treatment of Diffuse Intrinsic Pontine Glioma and Progressive or Refractory High-Grade Glioma.
D-Lactic acid
go.drugbank.com/drugs/DB03066ExperimentalThe concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
ASP-8731
go.drugbank.com/drugs/DB17696InvestigationalDeveloped by Mitobridge, it is being investigated for the treatment of sickle cell disease.[L46093]
Bacteroides thetaiotaomicron
go.drugbank.com/drugs/DB17879InvestigationalDeveloped by 4D Pharma, Thetanix, an oral formulation comprising lyophilized Bacteroides thetaiotaomicron, is being investigated for the treatment of Crohn’s disease.[A259892]
Pentosan polysulfate
go.drugbank.com/drugs/DB00686ApprovedInvestigationalPentosan polysulfate is a sulfated pentosyl polysaccharide with heparin-like properties.
Synonyms: 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULFATE, 4-O-METHYL-.ALPHA.-D-GLUCURONO-.BETA.-D-XYLAN, HYDROGEN SULPHATE