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Tavaborole
go.drugbank.com/drugs/DB09041ApprovedTavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to *Trichophyton rubrum* or *Trichophyton mentagrophytes … Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).
Synonyms: 5-Fluoro-2,1-benzoxaborol-1(3H)-ol, 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborolePoliovirus type 2 antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB10796ApprovedInvestigationalPoliovirus type 2 antigen is a suspension of poliovirus Type 2 (MEF-1) used in the active immunization of infants (as young as 6 weeks of age), children, and adults for the prevention of poliomyelitis … caused by poliovirus Type 2.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 1 ADET, TETRAXIM 0.5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADETSynonyms: Inactivated poliovirus type II, Poliovirus vaccine inactivated, type 2 (MEF-1)Spermidine
go.drugbank.com/drugs/DB03566InvestigationalIt is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine. … Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids.
Synonyms: N-(3-Aminopropyl)-1,4-butane-diamine, N-(3-aminopropyl)butane-1,4-diamineDexamethasone acetate
go.drugbank.com/drugs/DB14649ApprovedInvestigationalVet approvedCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions. … [T797,L10695,L14348] Developed in 1957, dexamethasone is structurally similar to other corticosteroids such as [hydrocortisone] and [prednisolone].
Mixtures: BAYCUTEN® N CREMA, BAYCUTEN® N CREMACategories: P-glycoprotein inducers, P-glycoprotein inhibitorsNisoldipine
go.drugbank.com/drugs/DB00401ApprovedNisoldipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: isobutyl methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylateMetrifonate
go.drugbank.com/drugs/DB11473ExperimentalVet approvedMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
Categories: Compounds used in a research, industrial, or household settingSynonyms: 1-Hydroxy-2,2,2-trichloroethylphosphonic acid dimethyl esterTromethamine
go.drugbank.com/drugs/DB03754ApprovedInvestigationalIt is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Amino-2-(hydroxymethyl)-1,3-propanediolRanpirnase
go.drugbank.com/drugs/DB04950InvestigationalRanpirnase is a ribonuclease enzyme found in <i>Rana pipiens</i> oocytes. It is being studied in the treatment of cancer. It is manufactured by Alfacell Corporation. … It is the first ribonuclease to enter cancer clinical trials.