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Secnidazole
go.drugbank.com/drugs/DB12834ApprovedInvestigationalSecnidazole is a second-generation 5-nitroimidazole antimicrobial agent. It is structurally related to other 5-nitroimidazoles, including DB00916 and DB00911, but displays improved oral absorption and a longer terminal elimination half-l...
Mixtures: GYNFLU® D TABLETAS, GYNFLU® D TABLETASCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsPantothenic acid
go.drugbank.com/drugs/DB01783ApprovedInvestigationalNutraceuticalVet approvedPantothenic acid is an ingredient in some hair and skin care products. … Only the dextrorotatory (D) isomer of pantothenic acid possesses biological activity. while the levorotatory (L) form may antagonize the effects of the dextrorotatory isomer.
Mixtures: VIL-Rx, Se-Tan PLUSSynonyms: D-pantothenic acidIsosorbide dinitrate
go.drugbank.com/drugs/DB00883ApprovedInvestigationalA vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme InhibitorsSynonyms: D-Isosorbide dinitrate, Dinitrato de isosorbida17-beta-hydroxysteroid dehydrogenase type 1
go.drugbank.com/bio_entities/BE0000194TargetEnzymeHumansConverts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2) (PubMed:8994190). Also has 20-alpha-HSD activity. Uses preferentially NADH
Synonyms: Estradiol 17-beta-dehydrogenase 1Estrone sulfate
go.drugbank.com/drugs/DB04574ApprovedEstrone sulfate (as estropipate) is a form of estrogen. It has several uses such as: alleviate symptoms of menopause as hormone replacement therapy, treatment some types of infertility, treatment of some conditions leading to underdevelo...
Categories: Estradiol Congeners, Cytochrome P-450 SubstratesRelugolix
go.drugbank.com/drugs/DB11853ApprovedInvestigational[A225926] In May 2021, the FDA approved the combination product made up of relugolix, [estradiol], and [norethindrone] under the market name Myfembree for the first once-daily treatment for the management
Categories: relugolix, estradiol and norethisterone, P-glycoprotein inhibitorsGentian violet cation
go.drugbank.com/drugs/DB00406ApprovedA dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.
Products: De LA Cruz Gentian VioletPramipexole
go.drugbank.com/drugs/DB00413ApprovedInvestigationalPramipexole is a drug used to treat the symptoms of Parkinson's Disease (PD). … Parkinson's Disease is one of the most common neurodegenerative disorders and causes a high level of disability in patients [A176855], leading to increased difficulty in performing activities of daily living due
Products: Nu-pramipexole, MIRAPEX ® ER 1.5 MG TABLETAS DE LIBERACIÓN PROLONGADA17-beta-hydroxysteroid dehydrogenase type 2
go.drugbank.com/bio_entities/BE0000006TargetEnzymeHumansOxidizes estradiol to estrone, testosterone to androstenedione, and dihydrotestosterone to 5alpha-androstan-3,17-dione. Also has 20-alpha-HSD activity … Catalyzes the NAD-dependent oxidation of the highly active 17beta-hydroxysteroids, such as estradiol (E2), testosterone (T), and dihydrotestosterone (DHT), to their less active forms and thus regulates
Synonyms: Estradiol 17-beta-dehydrogenase 2Biperiden
go.drugbank.com/drugs/DB00810ApprovedInvestigationalWithdrawnA muscarinic antagonist that has effects in both the central and peripheral nervous systems. It has been used in the treatment of arteriosclerotic, idiopathic, and postencephalitic parkinsonism. It has also been used to alleviate extrapy...
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: AKINETON® TABLETA DE LIBERACION PROLONGADA