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Lactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedIt is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3. … (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste.
Mixtures: PHYSIONEAL 40 DEXTROSE SOLUTION 1.5% w/v/15.0 mg/ml, LAFLEKS LAKTATLI RİNGER ÇÖZELTİSİ, 150 ML SETLİProducts: LAC HYDRIN LOCION, Lactimol - Crm 10%Satralizumab
go.drugbank.com/drugs/DB15762ApprovedInvestigationalSatralizumab is a recombinant humanized monoclonal antibody targeted against human interleukin-6 (IL-6) receptors, similar to [tocilizumab], which is produced in Chinese hamster ovary cells and based on … [L15536] Satralizumab is used in the treatment of neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune inflammatory disorder of the central nervous system (CNS) involving demyelinating lesions
Products: ENSPRYNG 120 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, ENSPRYNG 120 mg/1ml solution for injection in pre-filled syringeRamipril
go.drugbank.com/drugs/DB00178ApprovedInvestigationalRamipril is a prodrug belonging to the angiotensin-converting enzyme (ACE) inhibitor class of medications. It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
Mixtures: Ramipril/Amlodipin/HCT 1A Pharma 10 mg/10 mg/25 mg – Hartkapseln, Ramipril/Amlodipin/HCT 1A Pharma 10 mg/5 mg/25 mg – HartkapselnProducts: RAMIPRIL 1A PHARMA 10 MG, Ramipril 1A Pharma 10 mg - TablettenTriamcinolone
go.drugbank.com/drugs/DB00620ApprovedInvestigationalVet approved[L8255] Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain,[L8264] or first line as a topical treatment of corticosteroid responsive dermatoses. … Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis.
Mixtures: Aureocort 1 mg/g + 30 mg/g Salbe, LtCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersArsenic trioxide
go.drugbank.com/drugs/DB01169ApprovedInvestigationalIn general, arsenic is known to be a naturally toxic substance capable of eliciting a variety of dangerous adverse effects. … The enzyme thioredoxin reductase has recently been identified as a target for arsenic trioxide.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 10 ADET, LEUSENOX 10 MG/10 ML IV INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN AMPUL, 1 ADETVinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt is a third-generation vinca alkaloid. … A study was done on the clearance rate of vinorelbine on individuals with various single polymorphonuclear mutations.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 SubstratesProducts: VINELBINE INJECTION 10 MG/ML, NAVELBINE INJECTION 10 mg/mlPhenolphthalein
go.drugbank.com/drugs/DB04824ApprovedWithdrawnPhenolphthalein was withdrawn in Canada due to concerns with carcinogenicity in 1997.
International brands: Feen-a-mint gum, Feen-a-mint laxative mintsMixtures: Le 100 B, AGAROL M (EMULSION)Furazolidone
go.drugbank.com/drugs/DB00614InvestigationalVet approvedA nitrofuran derivative with antiprotozoal and antibacterial activity. Furazolidone binds bacterial DNA which leads to the gradual inhibition of monoamine oxidase.
International brands: Dependal-MCategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesSimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnThe overall SVR12 was 88% (44/50) in treatment-naïve patients with cirrhosis [L852]. … Sustained virologic response 12 weeks after planned end of treatment (SVR12) was achieved in 170/176 (97%) subjects without cirrhosis treated with 12 weeks simeprevir in combination with sofosbuvir (FDA
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsProducts: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADETVinblastine
go.drugbank.com/drugs/DB00570ApprovedInvestigationalAntitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, BSEP/ABCB11 Substrates with a Narrow Therapeutic IndexProducts: VINCABLAS® 10 MG/VIAL, VINBLASTINA SULFATO 10 MG