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Displaying results 571 - 580 of 10000 in total
  1. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    A compound formed in the liver from ammonia produced by the deamination of amino acids.

    Mixtures: Ti-U-lac Lotion, Ti-U-lac HC LotionProducts: Rea Lo 39, Rea Lo 40
  2. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.

    Mixtures: PIOGLITAZONE E METFORMINA EG, PIOGLITAZONE E METFORMINA EGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  3. Drug

    Alfuzosin

    go.drugbank.com/drugs/DB00346
    Approved

    Benign prostatic hyperplasia (BPH) refers to a benign growth or hyperplasia of the prostate and leads to lower urinary tract symptoms in men, such as urgency, frequency and changes to urine flow. … The prevalence of BPH is as high as 50%-60% for males in their 60's, and this prevalence increases to 80%-90% of those over 70.

    Synonyms: (±)-N-[3-[(4-amino-6,7-dimethoxy-2-quinazolinyl)methylamino]propyl]tetrahydro-2-furamide, N-[3-[(4-amino-6,7-dimethoxy-quinazolin-2-yl)- methyl-amino]propyl] tetrahydrofuran- 2-carboxamideCategories: Cytochrome P-450 Substrates, P-glycoprotein substrates
  4. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    Benzoyl peroxide is a commonly used drug in topical treatments for acne. … [L33249,L33264,L33269,L33299,L33314] It has been formulated as products with either a single active ingredient,[L33249,L33299] or with [erythromycin],[L33264] [clindamycin],[L33269] or [adapalene].

    Synonyms: Peróxido de benzoiloMixtures: OXIMIN 10 MG/G + 50 MG/G JEL,50 G, OXIMIN 10 MG/G + 50 MG/G JEL,25 G
  5. Drug

    Cloxacillin

    go.drugbank.com/drugs/DB01147
    ApprovedInvestigationalVet approved

    A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].

    Synonyms: (2S,5R,6R)-6-({[3-(2-chlorophenyl)-5-methylisoxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillinCategories: Heterocyclic Compounds, 2-Ring
  6. Drug

    Hydromorphone

    go.drugbank.com/drugs/DB00327
    ApprovedIllicitInvestigational

    Structurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … Hydromorphone is a pure opioid,[A176468] a semi-synthetic hydrogenated ketone derivative of [morphine] that has been available clinically since 1920.

    Synonyms: 6-Deoxy-7,8-dihydro-6-oxomorphine, 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-oneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  7. Drug

    Peginterferon Alfacon-2

    go.drugbank.com/drugs/DB19335
    Investigational

    Peginterferon Alfacon-2 is under investigation in clinical trial NCT06544551 (Efficacy and Safety Study of Peginterferon Alfacon-2 to Treat Chronic Hepatitis B Virus Infection).

    Synonyms: Peg-interferon Alfacon-2, Interferon .alpha.1 (synthetic), n-terminal 20-kilodalton pegylatedCategories: peginterferon alfacon-2
  8. Drug

    Momordica charantia fruit

    go.drugbank.com/drugs/DB14265
    Investigational

    Momordica charantia fruit is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Balsam Pear, Balsam Pear FruitProducts: Dangsim K-7
  9. Drug

    Captopril

    go.drugbank.com/drugs/DB01197
    ApprovedInvestigational

    ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS). Captopril may be used in the treatment of hypertension. … Captopril is a potent, competitive inhibitor of angiotensin-converting enzyme (ACE), the enzyme responsible for the conversion of angiotensin I (ATI) to angiotensin II (ATII).

    Synonyms: L-Captopril, D-2-methyl-3-mercaptopropanoyl-L-prolineMixtures: CAPTOPRIL E IDROCLOROTIAZIDE HEXAL, CAPTOPRIL E IDROCLOROTIAZIDE SANDOZ
  10. Drug

    Sulfate ion

    go.drugbank.com/drugs/DB14546
    Investigational

    Mixtures: Telom-X-geneSynonyms: Sulfate(2-), Sulfuric acid ion(2-)