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Displaying results 5791 - 5800 of 10000 in total
  1. Drug

    Uplarafenib

    go.drugbank.com/drugs/DB21661
    Experimental

    The usage of the INN stem '-rafenib' in the name indicates that Uplarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor. Uplarafenib has a monoisotopic molecular weight of 494.12 Da.

  2. Drug

    Fosrolapitant

    go.drugbank.com/drugs/DB21723
    Investigational

    The usage of the INN stem '-pitant' in the name indicates that Fosrolapitant is a neurokinin NK1​ (substance P) receptor antagonist. Fosrolapitant has a monoisotopic molecular weight of 654.16 Da.

  3. Drug

    Flezurafenib

    go.drugbank.com/drugs/DB21725
    Experimental

    Flezurafenib has a monoisotopic molecular weight of 456.16 Da. … The usage of the INN stem '-rafenib' in the name indicates that Flezurafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.

  4. Drug

    QRX-411

    go.drugbank.com/drugs/DB17868
    Experimental

    It addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.

  5. Drug

    AGRO100

    go.drugbank.com/drugs/DB04998
    Investigational

    AGRO100 is an oligonucleotide that functions as an aptamer and binds to nucleolin, a protein found intranuclear in all cells, but uniquely expressed on the surface of tumor cells. … Such binding leads to internalization of the complex, and a strong anti-proliferative response in the tumor cell.

  6. Drug

    Trastuzumab emtansine

    go.drugbank.com/drugs/DB05773
    ApprovedInvestigational

    Trastuzumab emtansine, formerly called Trastuzumab-DM1 (T-DM1) is a first-in-class HER2 antibody drug conjugate (ADC) comprised of Genentech's trastuzumab antibody linked to ImmunoGen's cell-killing agent … Trastuzumab emtansine is marketed under the brand name Kadcyla and is indicated for use in HER2-positive, metastatic breast cancer patients who have already used taxane and/or trastuzumab for metastatic

  7. Drug

    Nifurizone

    go.drugbank.com/drugs/DB19694
    Experimental

    The usage of the INN stem 'nifur-' in the name indicates that Nifurizone is a 5-nitrofuran derivative. Nifurizone has a monoisotopic molecular weight of 307.09 Da. … The usage of the INN stem '-zone' in the name indicates that Nifurizone is a anti-inflammatory analgesic, phenylbutazone derivative.

  8. Drug

    Onametostat

    go.drugbank.com/drugs/DB21480
    Investigational

    Onametostat has a monoisotopic molecular weight of 482.11 Da. … The usage of the INN stem '-metostat' in the name indicates that Onametostat is a histone N-methyltransferase inhibitor.

  9. Drug

    Nifurethazone

    go.drugbank.com/drugs/DB20112
    Experimental

    The usage of the INN stem 'nifur-' in the name indicates that Nifurethazone is a 5-nitrofuran derivative. Nifurethazone has a monoisotopic molecular weight of 269.11 Da. … The usage of the INN stem '-azone' in the name indicates that Nifurethazone is a anti-inflammatory analgesic, phenylbutazone derivative.

  10. Drug

    Dibekacin

    go.drugbank.com/drugs/DB13270
    Approved

    Dibekacin is an aminoglycoside antibiotic marketed in Japan [L5623].