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Fenoprofen
go.drugbank.com/drugs/DB00573ApprovedAn anti-inflammatory analgesic and antipyretic highly bound to plasma proteins. It is pharmacologically similar to aspirin, but causes less gastrointestinal bleeding.
PXS-4728A free base
go.drugbank.com/drugs/DB19177InvestigationalPXS-4728A free base is under investigation in clinical trial NCT05904717 (Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder).
Synonyms: Benzamide, 4-(((2e)-2-(aminomethyl)-3-fluoro-2-propen-1-yl)oxy)-n-(1,1-dimethylethyl)-Tandamine
go.drugbank.com/drugs/DB09192ExperimentalTandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).
CA-170
go.drugbank.com/drugs/DB15772InvestigationalCA-170 is a selective, small molecule inhibitor of PD-L1.
XR5944
go.drugbank.com/drugs/DB06364ExperimentalXR5944 is a DNA bis-intercalating anticancer drug. It has both intercalating and antineoplastic activities.
Nialamide
go.drugbank.com/drugs/DB04820ApprovedWithdrawnWithdrawn from the Canadian, US, and UK markets in 1963 due to interactions with food products containing tyrosine.
Synonyms: N-Isonicotinoyl-N'(beta-N-benzylcarboxamidoethyl)hydrazine, N-(2-(Benzylcarbamyl)ethylamino)isonicotinamideSparsomycin
go.drugbank.com/drugs/DB04222ExperimentalAn antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
GC012F
go.drugbank.com/drugs/DB22406InvestigationalGC012F is under investigation in clinical trial NCT06419166 (An Exploratory Clinical Study of GC012F Injection for Refractory gMG).
Botrytis cinerea
go.drugbank.com/drugs/DB10428ApprovedBotrytis cinerea is a fungus which can provoke allergic reactions. Botrytis cinerea extract is used in allergenic testing.
Mixtures: A Mold Mixture, A Mold MixtureNeurospora intermedia
go.drugbank.com/drugs/DB10438ApprovedNeurospora intermedia is a fungus which can provoke allergic reactions. Neurospora intermedia extract is used in allergenic testing.
Mixtures: A Mold Mixture, A Mold Mixture