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Displaying results 5821 - 5830 of 10000 in total
  1. Drug

    Flurazepam

    go.drugbank.com/drugs/DB00690
    ApprovedIllicit

    A benzodiazepine derivative used mainly as a hypnotic.

  2. Drug

    TRC093

    go.drugbank.com/drugs/DB06356
    Investigational

    TRC093 is a recombinant humanized IgG1k monoclonal antibody.

  3. Drug

    Thymectacin

    go.drugbank.com/drugs/DB05116
    Investigational

    Thymectacin was as efficacious as irinotecan, a drug recently approved for the treatment of 5-fluorouracil-resistant colon cancer. … Thymectacin is selectively active against tumor cells expressing high levels of thymidylate synthase (TS), a critical enzyme in DNA biosynthesis.

  4. Drug

    Ciluprevir

    go.drugbank.com/drugs/DB05868
    Investigational

    The compound, named BILN 2061, is an orally active inhibitor of the HCV NS3 protease and the first member of this new drug class to be tested in humans.

  5. Drug

    Adenosine 5'-[gamma-thio]triphosphate

    go.drugbank.com/drugs/DB02930
    Experimental

    A nucleoside triphosphate analogue that is ATP in which one of the oxygens attached to 3-phosphate group is replaced by sulfur.

    Synonyms: Adenosine 5-O-(3-thiotriphophate), Adenosine 5'-O-(3-thiotriphosphate)Categories: Compounds used in a research, industrial, or household setting
  6. Target

    Cytochrome P450 1A1

    go.drugbank.com/bio_entities/BE0003543
    EnzymeTargetHumans

    May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues. … Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation (PubMed:15041462, PubMed:18577768).

    Synonyms: Cytochrome P450 form 6
  7. Drug

    Ovatodiolide

    go.drugbank.com/drugs/DB19264
    Investigational

    Ovatodiolide is under investigation in clinical trial NCT04220411 (A Study for AR100DP1 in Mild to Moderate Atopic Dermatitis (AD)).

  8. Drug

    Metralindole

    go.drugbank.com/drugs/DB09306
    Experimental

    In Russia, this drug was investigated for potential antidepressant activity. … Metralindole, also known as Inkazan, is similar in structure and pharmacology to pirlindole. It functions as a reversible inhibitor of monoamine oxidase A.

  9. Drug

    Desmethylprodine

    go.drugbank.com/drugs/DB01478
    ExperimentalIllicit

    It has been listed as a Schedule I controlled drug in the United States, and thus is not used clinically. It is known to be a designer drug, synthesized in 1977, for the purpose of recreational use. … Desmethylprodine, a derivative of meperidine, is an opioid analgesic with the potency of morphine.

  10. Drug

    TC-6987

    go.drugbank.com/drugs/DB14854
    Investigational

    TC-6987 is under investigation in clinical trial NCT01296087 (TC-6987 for the Treatment of Mild to Moderate Asthma).