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Displaying results 5831 - 5840 of 10000 in total
  1. Drug

    PGX-100

    go.drugbank.com/drugs/DB06114
    Investigational

    It is a nearly nonanticoagulant heparin derivative that retains its anti-inflammatory activity. … PGX-100 is an intravenous dosage form of modified heparin.

  2. Drug

    Parecoxib

    go.drugbank.com/drugs/DB08439
    ApprovedInvestigational

    A letter of non-approval for parecoxib was issued by the FDA in 2005. … Parecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union.

    Synonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide
  3. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    A drug that has anti-inflammatory, antipyretic, and analgesic activities. It is especially effective in the treatment of ankylosing spondylitis. … It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication).

    Synonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedione
  4. Drug

    MC-1

    go.drugbank.com/drugs/DB05315
    Experimental

    Medicure's MC-1 drug is a cardio-protectant, designed to reduce the damage to the heart when arteries are blocked and when they are subsequently reopened after bypass surgery.

  5. Drug

    Flufenamic acid

    go.drugbank.com/drugs/DB02266
    Approved

    An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically.

  6. Drug

    Certociclib

    go.drugbank.com/drugs/DB21736
    Investigational

    Certociclib has a monoisotopic molecular weight of 365.14 Da. … Certociclib is a small molecule drug. Certociclib is under investigation in clinical trial NCT05252416 ((VELA) Study of BLU-222 in Advanced Solid Tumors).

  7. Drug

    CM4620

    go.drugbank.com/drugs/DB16466
    Investigational

    CM4620 (Zegocractin), is under investigation in multiple clinical trials, including NCT04195347 (pancreatitis due to asparaginase), NCT03709342 (PK/PD study in acute pancreatitis), NCT03401190 and NCT04681066

    Synonyms: N-(5-(6-CHLORO-2,2-DIFLUOROBENZO(D)(1,3)DIOXOL-5-YL)PYRAZIN-2-YL)-2-FLUORO-6-METHYLBENZAMIDE, BENZAMIDE, N-(5-(6-CHLORO-2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)-2-PYRAZINYL)-2-FLUORO-6-METHYL-
  8. Drug

    Bucainide

    go.drugbank.com/drugs/DB20650
    Experimental

    Bucainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Bucainide is a class I antiarrhythmic, procainamide and lidocaine derivative. … Bucainide has a monoisotopic molecular weight of 329.28 Da.

  9. Drug

    Cinuperone

    go.drugbank.com/drugs/DB19498
    Experimental

    Cinuperone has a monoisotopic molecular weight of 377.19 Da. … Cinuperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Cinuperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative.

  10. Drug

    Declenperone

    go.drugbank.com/drugs/DB19700
    Experimental

    Declenperone has a monoisotopic molecular weight of 381.19 Da. … Declenperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Declenperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative.