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Displaying results 581 - 590 of 10000 in total
  1. Drug

    Povidone

    go.drugbank.com/drugs/DB11061
    ApprovedInvestigationalWithdrawn

    The clinical effectiveness of [DB06812] on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with … It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier.

    Mixtures: PMS-artificial Tears Plus SolCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Digoxin

    go.drugbank.com/drugs/DB00390
    ApprovedInvestigational

    [A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … [L9143] This drug originates from the foxglove plant, also known as the _Digitalis_ plant[T610], studied by William Withering, an English physician and botanist in the 1780s.

    Categories: Compounds used in a research, industrial, or household settingProducts: PMS-digoxin
  3. Drug

    Bleomycin

    go.drugbank.com/drugs/DB00290
    ApprovedInvestigational

    It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors. Bleomycin A2 is used as the representative structure for Bleomycin. … A complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0).

    Products: Blenoxane Pws 15unit
  4. Drug

    Ampicillin

    go.drugbank.com/drugs/DB00415
    ApprovedInvestigationalVet approved

    Ampicillin is a semi-synthetic derivative of penicillin that functions as an orally active broad-spectrum antibiotic.

    Mixtures: PENBRITIN EX, AMPICILLINA E SULBACTAM IBIProducts: Penbritin Pws 250mg/5ml, Penbritin-125 Pws 125mg/vial
  5. Drug

    Felodipine

    go.drugbank.com/drugs/DB01023
    Approved

    Felodipine is the most potent CCB in use and is unique in that it exhibits fluorescent activity. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.

    International brands: Felodur ER, Plendil ERProducts: PLENDIL 2.5MG ER TABLET, PLENDIL 5 ER TABLETS (9MM)
  6. Drug

    Glyburide

    go.drugbank.com/drugs/DB01016
    ApprovedInvestigational

    [L8123] It is typically given to patients who cannot be managed with the standard first line therapy, [metformin]. … [A183617] Glyburide was granted FDA approval on 1 May 1984.[L8117] A formulation with metformin was granted FDA approval on on 31 July 2000.[L8120]

    Synonyms: 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamideCategories: Drugs Used in Diabetes
  7. Drug

    Citalopram

    go.drugbank.com/drugs/DB00215
    ApprovedInvestigational

    [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.

    Products: CITALOPRAM EG, PMS-citalopram
  8. Drug

    Allopurinol

    go.drugbank.com/drugs/DB00437
    ApprovedInvestigational

    It was initially approved by the FDA in 1966 [L5674] and is now formulated by several manufacturers [L5677]. … This disease has been well-documented in historical medical records and appears in the biographies of several prominent, historically recognized individuals [A175942].

    Products: PMS-allopurinol, ALLOPURINOLO EG
  9. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184781,A184808,A184817] ACEIs are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384]

    Synonyms: (S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-prolineMixtures: LISINOPRIL IDROCLOROTIAZIDE EG, LISINOPRIL IDROCLOROTIAZIDE EG
  10. Drug

    Tramadol

    go.drugbank.com/drugs/DB00193
    ApprovedInvestigational

    Tramadol differs from other traditional opioid medications in that it doesn't just act as a μ-opioid agonist, but also affects monoamines by modulating the effects of neurotransmitters involved in the … It is considered a Step 2 option on the World Health Organization's pain ladder and has about 1/10th of the potency of [morphine].

    Mixtures: Pat-tramadol/acet, PMS-tramadol-acetProducts: Ultram ER, Tramadol ER