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Displaying results 581 - 590 of 10000 in total
  1. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    However, this is no longer recommended for the majority of patients due to several clinical concerns including limited controlled trials supporting its use. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.

    Mixtures: SYNTHROID® 112 MCG TABLETAS, BITIRON 50 MCG/12.5 MCG TABLET, 100 ADETProducts: TABLETAS, TIROXIN ® 125 TABLETAS
  2. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Synonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamideProducts: ARAVA®TABLETAS RECUBIERTAS 100 MG., ARAVA® TABLETAS RECUBIERTAS 20 MG.
  3. Pathway

    Acylcarnitine (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123569
    Metabolic

    -1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine. … inner membrane to once again form (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoyl-CoA and L-carnitine. (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  4. Drug

    Ribociclib

    go.drugbank.com/drugs/DB11730
    ApprovedInvestigational

    Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali.

    Products: KISQALI 200 MG TABLETAS RECUBIERTAS, Kryxana 200mg Film-coated Tablets
  5. Drug

    Zafirlukast

    go.drugbank.com/drugs/DB00549
    Approved

    Zafirlukast is an oral leukotriene receptor antagonist (LTRA) for the maintenance treatment of asthma, often used in conjunction with an inhaled steroid and/or long-acting bronchodilator. … Zafirlukast blocks the action of the cysteinyl leukotrienes on the CysLT1 receptors, thus reducing constriction of the airways, build-up of mucus in the lungs and inflammation of the breathing passages

    Synonyms: 4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol-3-ylmethyl)-3-methoxy-N-o-tolylsulfonylbenzamideProducts: TABLETAS RECUBIERTAS, ACCOLATE 20 MG TABLETA RECUBIERTA.
  6. Drug

    Tacrolimus

    go.drugbank.com/drugs/DB00864
    ApprovedInvestigational

    It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. … Tacrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection.

    Products: TACROLIMUS EG, PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 1 MG
  7. Drug

    Lisinopril

    go.drugbank.com/drugs/DB00722
    ApprovedInvestigational

    [A184844] Lisinopril was granted FDA approval on 29 December 1987.[L8384] … Lisinopril is an angiotensin converting enzyme inhibitor (ACEI) used to treat hypertension, heart failure, and myocardial infarction.

    Mixtures: ALISINORM PLUS 20 MG/ 10 MG TABLETAS, LISINOPRIL E IDROCLOROTIAZIDE GITCategories: Agents Acting on the Renin-Angiotensin System, Compounds used in a research, industrial, or household setting
  8. Drug

    Macitentan

    go.drugbank.com/drugs/DB08932
    ApprovedInvestigational

    Macitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotoxicity. … A combination product (Opsynvi) comprising macitentan and [tadalafil] was approved in Canada in October 2021 for the treatment of PAH.[L39105] It was subsequently approved by the FDA in March 2024.

    Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASProducts: MACINTA® 10MG TABLETAS RECUBIERTAS, Opsumit 10mg Film-Coated Tablets
  9. Drug

    Trifluoperazine

    go.drugbank.com/drugs/DB00831
    Approved

    It is used as an antipsychotic and an antiemetic.

    Mixtures: CUAIT - D COMPRIMIDOS.Categories: Dopamine D2 Receptor Antagonists
  10. Drug

    Modafinil

    go.drugbank.com/drugs/DB00745
    ApprovedInvestigational

    The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular … Modafinil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy.

    Products: TABLETAS, TABLETAS