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Amitriptyline
go.drugbank.com/drugs/DB00321ApprovedInvestigationalAmitriptyline is a tricyclic antidepressant that has been used to treat depression for decades. ELAVIL, a previously approved branded product of amitriptyline, was first approved by the FDA in 1961. … [A259342] Amitriptyline has been investigated in the treatment of pain-related conditions, attributed to its analgesic properties.[A174661]
Mixtures: Etrafon A TabCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexPlantago seed
go.drugbank.com/drugs/DB11097ApprovedInvestigationalRegardless, this agent is most predominantly used as a gentle laxative agent in many parts of the world that is more commonly referred as psyllium or psyllium husk. … Its potential benefit in maintaining remission in ulcerative colitis has been studied [A27156].
Products: Hm-lax Cap 435mg, Easy Lax Pwr 480mgPyrithione
go.drugbank.com/drugs/DB06815ApprovedInvestigationalIn the crystalline state, it exists as a centrosymmetric dimer. Due to its dynamic fungistatic and bacteriostatic properties, pyrithione zinc is used to treat dandruff and seborrheic dermatitis. … Pyrithione zinc is commonly found as an active ingredient in OTC antidandruff topical treatments such as shampoos.
Synonyms: Pyridinethiol N-oxideProducts: Esika Men 2 En 1 Antidandruff Multi-action, L OCCITANE Anti-Dandruff Sensitive ScalpDeferiprone
go.drugbank.com/drugs/DB08826ApprovedInvestigationalDeferiprone is an oral iron chelator used as a second line agent in thalassemia syndromes when iron overload from blood transfusions occurs. … Thalassemias are a type of hereditary anaemia due a defect in the production of hemoglobin. As a result, erythropoiesis, the production of new red blood cells, is impaired.
Categories: Compounds used in a research, industrial, or household settingProducts: GPO-L-One Tablet 500mgOlmesartan
go.drugbank.com/drugs/DB00275ApprovedInvestigationalIn particular, heart failure is associated with chronic activation of RAAS, leading to inappropriate fluid retention, vasoconstriction, and ultimately a further decline in left ventricular function. … ARBs have been shown to have a protective effect on the heart by improving cardiac function, reducing afterload, increasing cardiac output and preventing ventricular hypertrophy and remodelling.
Mixtures: OLMEDOXTAN A®, OLMESAR/AMLOD AL 20/5MGCategories: Agents Acting on the Renin-Angiotensin SystemDarunavir
go.drugbank.com/drugs/DB01264ApprovedInvestigational[L9227] As a second-generation protease inhibitor, darunavir is designed to combat resistance to standard HIV therapy.[A2278,A2281] It was initially approved by the FDA in 2006. … [L9227] Darunavir is being studied as a possible treatment for SARS-CoV-2, the coronavirus responsible for COVID-19, due to in vitro evidence supporting its ability to combat this infection.
Synonyms: (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-((1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl)carbamate, (3R,3aS,6aR)-tetrahydro-2H-furo[2,3-b]furan-3-yl (2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamateMixtures: VIRONTAR N COMPRIMIDOS RECUBIERTOS, VIRONTAR N COMPRIMIDOS RECUBIERTOSLymphadenopathy
go.drugbank.com/conditions/DBCOND0006524Drugs: Interferon alfa-2bSynonyms: LA - LymphadenopathyAlendronic acid
go.drugbank.com/drugs/DB00630ApprovedInvestigationalAlendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].
Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, ACIDO ALENDRONICO E COLECALCIFEROLO EGProducts: ALENDRONATO EG, Gen-alendronateMirtazapine
go.drugbank.com/drugs/DB00370ApprovedInvestigationalMirtazapine is a tetracyclic _piperazino-azepine_ antidepressant agent that was initially approved for the treatment of major depressive disorder (MDD) in the Netherlands in 1994. … [A178144,L6160] In addition to its beneficial effects in depression, mirtazapine has been reported to be efficacious in the off-label management of various other conditions.
Synonyms: 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepineProducts: MIRTAZAPINA EG, MIRTAZAPINA EG STADACholecalciferol
go.drugbank.com/drugs/DB00169ApprovedInvestigationalNutraceuticalAppropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation … Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight [L5689].
Mixtures: Escavite Lq, L-Methyl PNV DHAProducts: COLECALCIFEROLO EG, L-VIT D3 5000