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Displaying results 581 - 590 of 10000 in total
  1. Drug

    Palbociclib

    go.drugbank.com/drugs/DB09073
    ApprovedInvestigational

    It is a second generation cyclin-dependent kinase inhibitor[A176798] selected from a group of pyridopyrimidine compounds due to its favorable physical and pharmaceutical properties. … Palbociclib is a piperazine pyridopyrimidine[A176792] that acts in the cell cycle machinery.

    Synonyms: 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-8h-pyrido(2,3-d)pyrimidin-7-one, 6-acetyl-8-cyclopentyl-5-methyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7(8H)-oneProducts: REAMPLA® 75 MG TABLETAS RECUBIERTAS, REAMPLA® 125 MG TABLETAS RECUBIERTAS
  2. Drug

    Paroxetine

    go.drugbank.com/drugs/DB00715
    ApprovedInvestigational

    [L7712,L7715] A unique feature of this drug is that it is highly potent and selective in its inhibition of serotonin reuptake and has little effect on other neurotransmitters. … [T653] It was approved by the FDA in the early 1990s and marketed by SmithKline Beecham.

    Products: PAROXETINA EG, PAROXETINA EG STADA
  3. Drug

    Clomifene

    go.drugbank.com/drugs/DB00882
    ApprovedInvestigational

    A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue.

    Synonyms: 2-(4-(2-chloro-1,2-diphenylethenyl)phenoxy)-N,N-diethylethanamineProducts: ZIMAQUIN50 MG TABLETAS, TOCOFENO 50 MG TABLETAS
  4. Drug

    Fulvestrant

    go.drugbank.com/drugs/DB00947
    ApprovedInvestigational

    It is an estrogen receptor antagonist with no agonist effects, which works both by down-regulating and by degrading the estrogen receptor. … Fulvestrant is a drug treatment of hormone receptor (HR)-positive metastatic breast cancer in post-menopausal women with disease progression following anti-estrogen therapy.

    Products: FULVESTRANT DR. REDDY'S, FULVESTRANT 250 MG/5ML SOLUCION INYECTABLE EN JERIGA PRECARGADA
  5. Pathway

    Acylcarnitine (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine

    smpdb.ca/view/SMP0123478
    Metabolic

    ,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine. … (4Z,7Z,10S,11E)-10-hydroxy-12-[(1S,2R,5S)-5-hydroxy-3-oxo-2-[(2Z)-pent-2-en-1-yl]cyclopentyl]dodeca-4,7,11-trienoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Drug

    Nitroprusside

    go.drugbank.com/drugs/DB00325
    ApprovedInvestigational

    Nitroprusside serves as a source of nitric oxide, a potent peripheral vasodilator that affects both arterioles and venules (venules more than arterioles). Nitroprusside is often administered intravenously to patients who are experiencing...

    Categories: Arteriolar Smooth Muscle, Agents Acting On, Compounds used in a research, industrial, or household settingProducts: NITROPRUSIATO DE SODIO, NITROPRUSIATO DE SODIO USP 25MG/ML
  7. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide was approved by FDA and in many other countries (e.g., Canada, Europe) in 1999.

    Synonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamideProducts: ARAVA®TABLETAS RECUBIERTAS 100 MG., ARAVA® TABLETAS RECUBIERTAS 20 MG.
  8. Drug

    Levothyroxine

    go.drugbank.com/drugs/DB00451
    ApprovedInvestigational

    However, this is no longer recommended for the majority of patients due to several clinical concerns including limited controlled trials supporting its use. … [F4633] T<sub>4</sub> and T<sub>3</sub> act on nearly every cell of the body, but have a particularly strong effect on the cardiac system.

    Mixtures: SYNTHROID® 112 MCG TABLETAS, BITIRON 50 MCG/12.5 MCG TABLET, 100 ADETProducts: TABLETAS, TIROXIN ® 125 TABLETAS
  9. Drug

    Ribociclib

    go.drugbank.com/drugs/DB11730
    ApprovedInvestigational

    Ribociclib was approved by the FDA in March 2017 under the brand name Kisqali.

    Products: KISQALI 200 MG TABLETAS RECUBIERTAS, Kryxana 200mg Film-coated Tablets
  10. Drug

    Lecithin, soybean

    go.drugbank.com/drugs/DB14161
    Investigational

    The emulsifying and surfactant properties are useful in food additives and for forming organogels (gels).

    Synonyms: Lecithins, soya, Soya lecithinsProducts: Essentiale Forte N