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Displaying results 5911 - 5920 of 7017 in total
  1. Drug

    HPV-16 trojan peptide vaccine

    go.drugbank.com/drugs/DB17496
    Investigational

    CD4 and CD8 T cell responses. … HPV-16 trojan peptide vaccine is an investigational cancer immunotherapy consisting of a novel Trojan peptide complex, composed of human papilloma virus 16 (HPV 16) epitopes, to stimulate antigen-specific

  2. Drug

    ABBV-514

    go.drugbank.com/drugs/DB17586
    Investigational

    ABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]

  3. Drug

    Oral Polio Vaccine

    go.drugbank.com/drugs/DB15864
    Investigational

    The oral polio vaccine (OPV) is a live attenuated vaccine containing a mixture of one or more strains of poliovirus serotypes. … After administration, OPV strains extensively multiply in the intestinal tract, becoming widely spread in the community to immunize a sizable proportion of those unvaccinated in the population[A220163]

  4. Drug

    Marbofloxacin

    go.drugbank.com/drugs/DB11426
    ExperimentalVet approved

    Marbofloxacin is a carboxylic acid, part of the third generation of antibiotic fluoroquinolones. It is used in veterinary medicine. … A formulation of marbofloxacin combined with clotrimazole and dexamethasone is available under the name Aurizon.

  5. Drug

    Bicuculline

    go.drugbank.com/drugs/DB11562
    Experimental

    Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. … It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

    Categories: GABA-A Receptor Antagonists
  6. Drug

    Ontuxizumab

    go.drugbank.com/drugs/DB16270
    Investigational

    Ontuxizumab is a humanized monoclonal antibody that targets endosialin or tumour endothelial marker 1 (TEM-1). … It is under investigation in clinical trial NCT01574716 (Sarcoma Study of Morab-004 Utilization: Research and Clinical Evaluation).

  7. Drug

    Collagen-polyvinylpyrrolidone

    go.drugbank.com/drugs/DB16525
    Investigational

    Collagen-polyvinylpyrrolidone is a copolymer generated from a mixture of type I collagen and low-molecular-weight PVP that has undergone γ irradiation[A227733]. … It is characterized by antifibrotic, fibrolytic, and immunomodulatory properties[A227733].

  8. Drug

    Ultevursen

    go.drugbank.com/drugs/DB17835
    Investigational

    Ultevursen is a single-stranded RNA-based oligonucleotide targeting exon 13 of the USH2A gene that encodes usherin. … It was developed by ProQR Therapeutics and is being investigated for the treatment of retinitis pigmentosa.

  9. Drug

    Choline alfoscerate

    go.drugbank.com/drugs/DB04660
    Investigational

    A component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. … (From Stedman, 26th ed) It counteracts the effects of urea on enzymes and other macromolecules. [PubChem]

  10. Drug

    Clofutriben

    go.drugbank.com/drugs/DB21636
    Investigational

    Clofutriben is a small molecule drug. Clofutriben is under investigation in clinical trial NCT05307328 (SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome). … Clofutriben has a monoisotopic molecular weight of 424.09 Da.