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Displaying results 5921 - 5930 of 8696 in total
  1. Drug

    ARC183

    go.drugbank.com/drugs/DB05124
    Experimental

    The key advantage of ARC183 compared to other thrombin inhibitors is its rapid onset of action and short half-life, giving it the potential to be an ideal agent for medical procedures that require rapid

  2. Drug

    TRO40303

    go.drugbank.com/drugs/DB16031
    Investigational

    TRO40303 is under investigation in clinical trial NCT01374321 (Safety and Efficacy Study of TRO40303 for Reduction of Reperfusion Injury in Patients Undergoing Percutaneous Coronary Intervention for Acute

  3. Drug

    Brivanib

    go.drugbank.com/drugs/DB11958
    Investigational

    Brivanib is under investigation for the treatment of HepatoCellular Carcinoma. … Brivanib has been investigated for the treatment of Solid Tumors, Hepato Cellular Carcinoma (HCC), and Metastatic Colorectal Cancer (MCRC).

  4. Drug

    5-fluorotryptophan

    go.drugbank.com/drugs/DB03314
    Experimental

    5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.

  5. Drug

    R1204

    go.drugbank.com/drugs/DB05118
    Experimental

    R1204 is G-protein-coupled receptor modulator. It is developed for the treatment of depression.

  6. Target

    Transforming growth factor beta activator LRRC32

    go.drugbank.com/bio_entities/BE0014554
    TargetHumans

    Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed:19651619, PubMed:19750484, PubMed:22278742). As...

    Synonyms: Leucine-rich repeat-containing protein 32Function: receptor ligand inhibitor activity
  7. Drug

    Rivanicline

    go.drugbank.com/drugs/DB05855
    Experimental

    It was originally developed as a potential treatment for Alzheimer's disease for its nootropic effects but has also been found to inhibit the production of Interleukin-8. … It has subsequently been developed as a potential anti-inflammatory treatment for ulcerative colitis.

  8. Drug

    Insulin pork

    go.drugbank.com/drugs/DB00071
    Approved

    Insulin isolated from pig pancreas. Composed of alpha and beta chains, processed from pro-insulin. Forms a hexameric structure.

    Categories: Insulins and Analogues for Injection, Fast-Acting, Cytochrome P-450 CYP1A2 Inducers
  9. Drug

    Etuvetidigene Autotemcel

    go.drugbank.com/drugs/DB17593
    ApprovedInvestigational

    Etuvetidigene autotemcel is an autologous gene therapy which includes hematopoietic stem cells (HSCs) that have been genetically modified ex vivo.

  10. Drug

    Sofpironium

    go.drugbank.com/drugs/DB19325
    Approved

    [L51108,L51109] Sofpironium bromide (Sofdra) was approved by the FDA in June 2024 for the topical treatment of primary axillary hyperhidrosis.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors