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Displaying results 5941 - 5950 of 10000 in total
  1. Pathway

    Cardiolipin Biosynthesis CL(20:2(11Z,14Z)/20:3(11Z,14Z,17Z)/20:2(11Z,14Z)/18:2(9Z,12Z))

    smpdb.ca/view/SMP0248507
    Metabolic

    Third, the enzyme 1-acyl-sn-glycerol-3-phosphate acyltransferase converts LPA into phosphatidic acid (PA or 1,2-diacyl-sn-glycerol 3-phosphate) by esterifying an acyl-group to the sn-2 position of the

    Drugs: NADH · Cytidine-5'-Triphosphate · sn-glycerol 3-phosphate · Pyrophosphoric acid · Dihydroxyacetone phosphate
    Enzymes: Phosphatidate cytidylyltransferase 2
  2. Drug

    Acemetacin

    go.drugbank.com/drugs/DB13783
    ApprovedInvestigational

    Acemetacin is a carboxymethyl ester of indometacin. … [A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E.

    Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: ACETUDIL FORTE 60 MG KAPSÜL, 20 ADET, RANTUDIL FORTE 60 MG KAPSUL, 20 ADET
  3. Drug

    Sevelamer

    go.drugbank.com/drugs/DB00658
    ApprovedInvestigational

    Sevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.

    Categories: Compounds used in a research, industrial, or household settingProducts: <html>RENALAMER CO<sub>3</sub> 800 MG FILM TABLET, 180 ADET</html>, RENVELA 2,4 G ORAL SÜSPANSIYON IÇIN TOZ, 60 SAŞE
  4. Drug

    Benzoyl peroxide

    go.drugbank.com/drugs/DB09096
    ApprovedInvestigational

    Benzoyl peroxide is a commonly used drug in topical treatments for acne. … [A234059,A234064,A234069] Benzoyl peroxide, in combination with erythromycin, was granted FDA approval on 26 October 1984.[L33264]

    Mixtures: OXIMIN 10 MG/G + 50 MG/G JEL,25 G, OXIMIN 10 MG/G + 50 MG/G JEL,50 GProducts: BENZAC(R) AC 2 1/2, Dual-shave 2 In 1
  5. Drug

    Epoprostenol

    go.drugbank.com/drugs/DB01240
    ApprovedInvestigational

    A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from prostaglandin endoperoxides in human vascular tissue.

    Synonyms: Prostaglandin X, Prostaglandin I2Categories: Prostaglandins I
  6. Drug

    Suvorexant

    go.drugbank.com/drugs/DB09034
    ApprovedInvestigational

    Suvorexant is a selective dual antagonist of orexin receptors OX1R and OX2R that promotes sleep by reducing wakefulness and arousal. It has been approved for the treatment of insomnia.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: BELSOMRA® 20 MG, BELSOMRA® 15 MG
  7. Drug

    Basiliximab

    go.drugbank.com/drugs/DB00074
    ApprovedInvestigational

    A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also … and mouse heavy and light chain variable region genes encoding the RFT5 antibody that binds selectively to the IL-2R alpha.

    Categories: Interleukin-2 Receptor Antagonist, Interleukin-2 Receptor Blocking AntibodyProducts: SIMULECT FOR INJECTION 20 mg/vial, SIMULECT® LIOFILIZADO PARA INYECCION 20 MG/VIAL
  8. Drug

    Tafluprost

    go.drugbank.com/drugs/DB08819
    Approved

    Chemically, tafluprost is a fluorinated analog of prostaglandin F2-alpha. Tafluprost was approved for use in the U.S. on February 10, 2012. … A prostaglandin analogue ester prodrug used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

    Mixtures: TAPCOM-S ophthalmic solution 15 micrograms/ml + 5 mg/ml, solution in single-dose container, Taptiqom 15 Mikrogramm/ml + 5 mg/ml Augentropfen, Lösung im EinzeldosisbehältnisProducts: SAFLUTAN®, TAFLOTAN-S OPHTHALMIC SOLUTION 0.0015%
  9. Drug

    Hepatitis B Vaccine (Recombinant)

    go.drugbank.com/drugs/DB11627
    ApprovedInvestigationalWithdrawn

    In Asia, infection often occurs early in life, leading to a hepatitis B marker prevalence of more than 70% in the general population and a carrier rate of up to 20%. … The hepatitis B virus induces a severe form of viral hepatitis. Other causative agents are hepatitis A virus, and the non-A, non-B hepatitis viruses.

    Synonyms: Hepatitis B antigen, Hepatitis B VaccineSalts: Hepatitis B virus subtype ADW HBSAG surface protein antigen, Hepatitis B virus subtype ADW2 HBSAG surface protein antigen
  10. Drug

    Clorazepic acid

    go.drugbank.com/drugs/DB00628
    ApprovedIllicit

    Similar to other benzodiazepines, the active metabolite of clorazepate enhances the binding of gamma-aminobutyric acid (GABA) to the GABA type A (GABA-A) receptor, which promotes channel opening and neuronal … Clorazepic acid (clorazepate) is a water-soluble benzodiazepine with muscle-relaxant and anticonvulsant actions effective in the treatment of anxiety.

    Synonyms: 7-chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acidInternational brands: Zetran-5