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Methylprednisone
go.drugbank.com/drugs/DB12952ApprovedInvestigationalWithdrawnMethylprednisone has been used in trials studying the treatment of Leukemia, Rheumatoid Arthritis, Renal Transplantation, Kidney Transplantation, and Acute Lymphocytic Leukemia, among others.
Imsidolimab
go.drugbank.com/drugs/DB16658InvestigationalImsidolimab is under investigation in clinical trial NCT03633396 (A Study to Evaluate the Efficacy and Safety of ANB019 in Subjects With Palmoplantar Pustulosis).
Pudexacianinium
go.drugbank.com/drugs/DB19161InvestigationalPudexacianinium is under investigation in clinical trial NCT05754333 (A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery).
Synonyms: 3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-2-((1E)-2-((3E)-3-((2E)-2-(3-(3-((3-(CYCLOMALTOHEPTAOS-21-O-YL)PROPYL)AMINO)-3-OXOPROPYL)-1,1-DIMETHYL-1,3-DIHYDRO-2H-BENZO(E)INDOL-2-YLIDENE, )-1,1-dimethyl-1h-benz(e)indolium ionATR-04
go.drugbank.com/drugs/DB26782InvestigationalATR-04 is under investigation in clinical trial NCT04731259 (Study to Evaluate the Safety of ATR-04).
TMC-310911
go.drugbank.com/drugs/DB15623InvestigationalTMC-310911 (also known as ASC-09) is a novel investigational protease inhibitor (PI) that is structurally similar to the currently available [darunavir]. … TMC-310911 has shown marked activity against a variety of HIV-1 strains, including multi-PI-resistant strains, and may be less likely to generate resistance, making it a potentially desirable therapy for
Linvencorvir
go.drugbank.com/drugs/DB21544InvestigationalThe usage of the INN stem '-corvir' in the name indicates that Linvencorvir is a core protein (Cp) inhibitor. … Linvencorvir is under investigation in clinical trial NCT04225715 (A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B).
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide
go.drugbank.com/drugs/DB08559ExperimentalThis compound belongs to the penicillins. … from the sulfur atom at position 1].
KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
Alvespimycin
go.drugbank.com/drugs/DB12442InvestigationalIn comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic liability, lower plasma protein binding, increased water solubility … It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.
Oglufanide
go.drugbank.com/drugs/DB05779InvestigationalOglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection. … Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before