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Displaying results 51 - 60 of 485 in total
  1. Target

    Fatty acid metabolism regulator protein

    go.drugbank.com/bio_entities/BE0004232
    TargetEscherichia coli (strain K12)

    Represses transcription of at least eight genes required for fatty acid transport and beta-oxidation including fadA, fadB, fadD, fadL and fadE (PubMed:9388199). … Activates transcription of at least three genes required for unsaturated fatty acid biosynthesis: fabA, fabB and iclR, the gene encoding the transcriptional regulator of the aceBAK operon encoding the

    Polypeptides: Fatty acid metabolism regulator protein
  2. Target

    N-acylethanolamine-hydrolyzing acid amidase

    go.drugbank.com/bio_entities/BE0009156
    TargetHumans

    Degrades bioactive fatty acid amides to their corresponding acids, with the following preference: N-palmitoylethanolamine > N-myristoylethanolamine > N-lauroylethanolamine = N-stearoylethanolamine > N-arachidonoylethanolamine … Also exhibits weak hydrolytic activity against the ceramides N-lauroylsphingosine and N-palmitoylsphingosine (PubMed:15655246)

    Polypeptides: N-acylethanolamine-hydrolyzing acid amidaseSynonyms: Acid ceramidase-like protein
  3. Target

    Neutral amino acid transporter A

    go.drugbank.com/bio_entities/BE0000480
    TargetHumans

    In a tri-substrate transport cycle, exchanges neutral amino acids between the extracellular and intracellular compartments, coupled to the inward cotransport of at least one sodium ion (PubMed:24808181 … Displays sodium- and amino acid-dependent but uncoupled channel-like anion conductance with a preference SCN(-) > NO3(-) > I(-) > Cl(-) (PubMed:8910405)

    Polypeptides: Neutral amino acid transporter AFunction: amino acid transmembrane transporter activity
  4. Target

    Cationic amino acid transporter 2

    go.drugbank.com/bio_entities/BE0000562
    TargetTransporterHumans

    Functions as a permease involved in the transport of the cationic amino acids (L-arginine, L-lysine, L-ornithine and L-homoarginine); the affinity for its substrates differs between isoforms created by

    Polypeptides: Cationic amino acid transporter 2Synonyms: Low affinity cationic amino acid transporter 2
  5. Target

    Retinoic acid-induced protein 3

    go.drugbank.com/bio_entities/BE0000697
    TargetHumans

    This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G protein signaling pathways. Functions as a negative modulator of EGFR signaling (By similarity). … Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.

    Polypeptides: Retinoic acid-induced protein 3Synonyms: Retinoic acid-induced gene 1 protein
  6. Target

    Excitatory amino acid transporter 3

    go.drugbank.com/bio_entities/BE0001054
    TargetTransporterHumans

    Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:26690923, PubMed:8857541). … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:21123949, PubMed:26690923, PubMed:33658209, PubMed:7521911, PubMed

    Polypeptides: Excitatory amino acid transporter 3Synonyms: Excitatory amino-acid carrier 1, Neuronal and epithelial glutamate transporter
  7. Target

    Uric acid degradation bifunctional protein

    go.drugbank.com/bio_entities/BE0001313
    TargetBacillus sp. (strain TB-90)

    Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline … (OHCU) to (S)-allantoin (By similarity).

    Polypeptides: Uric acid degradation bifunctional protein
  8. Target

    Fatty acid-binding protein, brain

    go.drugbank.com/bio_entities/BE0001821
    CarrierTargetHumans

    It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)

    Polypeptides: Fatty acid-binding protein, brainSynonyms: Fatty acid-binding protein 7, Brain-type fatty acid-binding protein
  9. Target

    Fatty acid-binding protein 5

    go.drugbank.com/bio_entities/BE0001984
    CarrierTargetHumans

    Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. … Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind.

    Polypeptides: Fatty acid-binding protein 5Synonyms: Fatty acid-binding protein, epidermal, Epidermal-type fatty acid-binding protein
  10. Target

    Branched-chain-amino-acid aminotransferase

    go.drugbank.com/bio_entities/BE0002016
    TargetEscherichia coli (strain K12)

    Acts on leucine, isoleucine and valine.

    Polypeptides: Branched-chain-amino-acid aminotransferaseFunction: branched-chain-amino-acid transaminase activity