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Displaying results 51 - 60 of 176 in total
  1. Target

    Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1

    go.drugbank.com/bio_entities/BE0018277
    TargetHumans

    Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). … Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity)

    Polypeptides: Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1Synonyms: Leucine-rich repeat and immunoglobulin domain-containing protein 1
  2. Target

    Casein

    go.drugbank.com/bio_entities/BE0010107
    CarrierTargetBovine

    Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. … Important role in determination of the surface properties of the casein micelles.

    Polypeptides: Beta-casein, Kappa-casein
  3. Target

    Kappa-casein

    go.drugbank.com/bio_entities/BE0009420
    TargetHumans

    Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk

    Polypeptides: Kappa-casein
  4. Target

    Casein kinase II subunit beta

    go.drugbank.com/bio_entities/BE0005435
    TargetHumans

    Regulatory subunit of casein kinase II/CK2.

    Polypeptides: Casein kinase II subunit beta
  5. Target

    Adiponectin receptor

    go.drugbank.com/bio_entities/BE0010287
    TargetHumans

    Required for normal glucose and fat homeostasis and for maintaining a normal body weight. … Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis.

    Synonyms: Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member I
  6. Target

    Casein kinase II subunit alpha'

    go.drugbank.com/bio_entities/BE0003984
    TargetHumans

    Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8 (PubMed:12631575, PubMed:19387551, PubMed:19387552). … Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function (PubMed:19387550).

    Polypeptides: Casein kinase II subunit alpha'
  7. Target

    Casein kinase I isoform alpha

    go.drugbank.com/bio_entities/BE0009427
    TargetHumans

    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (PubMed:11955436, PubMed:1409656, PubMed:18305108, PubMed:23902688). … May phosphorylate PER1 and PER2 (By similarity). May play a role in segregating chromosomes during mitosis (PubMed:1409656).

    Polypeptides: Casein kinase I isoform alpha
  8. Target

    Casein kinase II subunit alpha

    go.drugbank.com/bio_entities/BE0001209
    TargetHumans

    Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8 (PubMed:16193064). … Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3 (PubMed:16193064).

    Polypeptides: Casein kinase II subunit alpha
  9. Target

    Casein kinase I isoform epsilon

    go.drugbank.com/bio_entities/BE0003512
    TargetHumans

    Controls PER1 and PER2 nuclear transport and degradation (By similarity). Inhibits cytokine-induced granuloytic differentiation (PubMed:15070676) … Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates (Probable).

    Polypeptides: Casein kinase I isoform epsilon
  10. Target

    Casein kinase I isoform gamma-3

    go.drugbank.com/bio_entities/BE0003958
    TargetHumans

    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins.

    Polypeptides: Casein kinase I isoform gamma-3