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Haloperidol
go.drugbank.com/drugs/DB00502ApprovedInvestigational(mainly D2), particularly within the mesolimbic and mesocortical systems of the brain. … Dopamine-antagonizing medications such as haloperidol are though to improve psychotic symptoms and states that are caused by an over-production of dopamine, such as schizophrenia, which is theorized to
Categories: Dopamine D2 Receptor Antagonists, Cytochrome P-450 SubstratesProducts: Nu-haloperidol, HALOPERIDOL TABLETAS DE 10 MGFexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigationalantihistamines, such as [diphenhydramine], which readily bind to off-targets that contribute to side effects such as sedation. … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Mixtures: Allegra D-12 Hour, Allegra-DProducts: FEXU AD ®, Dg Health Aller EaseOxybutynin
go.drugbank.com/drugs/DB01062ApprovedInvestigationalDue to its urinary symptoms that include nocturia, urgency, and frequency, this condition causes social embarrassment and a poor quality of life. … It is often used as first-line therapy for OAB.[A185990]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: LYRINEL TABLETAS DE 15 MG, DITRO 15 MG TABLETAS DE LIBERACION CONTROLADAAcetylcysteine
go.drugbank.com/drugs/DB06151ApprovedInvestigationalAcetylcysteine is an antioxidant and glutathione inducer indicated for mucolytic therapy and the treatment of [acetaminophen] overdose. … [L31378,L31383,L31388,L31478] Acetylcysteine has also been studied for a wide variety of off-label indications with mixed results.
Mixtures: AMINOPLASMAL-15% INFUSION, AMINOPLASMAL 15% IN 500ML GLASS BOTTLECategories: Compounds used in a research, industrial, or household settingAlbuterol
go.drugbank.com/drugs/DB01001ApprovedInvestigationalVet approvedThe R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity. … Salbutamol is formulated as a racemic mixture of the R- and S-isomers.
Mixtures: AXOL DUO, Ibicar S (Salbutamol 100 mcg/actuation and Beclometasone 50 mcg/actuation) Pressurised InhalationCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsZinc sulfate
go.drugbank.com/drugs/DB09322ApprovedInvestigationalIt is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system. … Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol".
Mixtures: IROZINC ŞURUP ,100 ML, FERROZINC SURUP, 100 MLProducts: SULFATO DE ZINC 2MG/ML SOLUCION ORAL SABOR A CEREZA Y SABOR A CHICLE., CHINKO 15 MG/5 ML SURUP, 100 MLMoclobemide
go.drugbank.com/drugs/DB01171ApprovedInvestigationalA reversible monoamine oxidase inhibitor (MAOI) selective for isoform A (RIMA) used to treat major depressive disorder. … Due to negligible anticholinergic and antihistaminic actions, moclobemide has been better tolerated than tri- or heterocyclic antidepressants [A31901].
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Monoamine Oxidase A InhibitorsProducts: MOCLOBEMID-NEURAX 150 MG, Aurorix 150 mg - FilmtablettenPosaconazole
go.drugbank.com/drugs/DB01263ApprovedInvestigationalVet approvedPosaconazole is a triazole antifungal drug that is used to treat invasive infections by Candida species and Aspergillus species in severely immunocompromised patients.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsProducts: POSACONAZOLE DR. REDDY'S (Posaconazole 100 mg Modified Release tablets), POSACONAZOLO DR. REDDY'SRoxithromycin
go.drugbank.com/drugs/DB00778ApprovedInvestigationalWithdrawnIt is marketed in Australia as a treatment for respiratory tract, urinary and soft tissue infections. … Roxithromycin is a semi-synthethic macrolide antibiotic that is structurally and pharmacologically similar to [erythromycin], [azithromycin], or [clarithromycin].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InhibitorsInternational brands: Roxl-150, Roxy-150Diltiazem
go.drugbank.com/drugs/DB00343ApprovedInvestigational[T28] Being a potent vasodilator, diltiazem is used clinically as an antihypertensive, anti-arrhythmic, and as an anti-anginal agent [L6289] for the management of cardiovascular conditions such as hypertension … Diltiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InhibitorsSynonyms: d-cis-diltiazem