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Stiripentol
go.drugbank.com/drugs/DB09118ApprovedInvestigational[A19739] Approved in the US, Canada, and Europe, stiripentol is used to treat seizures associated with Dravet syndrome.[L880,L42500,L42510] It is marketed under the brand name Diacomit.
Tetrodotoxin
go.drugbank.com/drugs/DB05232InvestigationalAn aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order tetraodontiformes, which are eaten. … Tetrodotoxin is being investigated by Wex Pharmaceuticals for the treatment of chronic and breakthrough pain in advanced cancer patients as well as for the treatment of opioid dependence.
Carbazochrome
go.drugbank.com/drugs/DB09012ApprovedWithdrawnCarbazochrome has been investigated for use in the treatment of non-surgical acute uncomplicated hemorrhoids in a mixture with [DB13124], and this combination therapy demonstrated efficacy and safe tolerability … It is not FDA-approved but is available as tablets or IM/SC injections in the treatment of hemorrhages in a number of countries.
International brands: Hemosin K, Ophthalm KZotepine
go.drugbank.com/drugs/DB09225ApprovedWithdrawnIt was designed and synthesized by Fujisawa Pharmaceutical Co Ltd.[A31855] It has been used as an antipsychotic in Japan, India and some places in Europe like UK and Germany since 1980's. … In 1993, it was classified as inactive drug substance (Status I, Type II) and in 1995 the FDA studied the manufacturing procedures of Zotepine tablets in Germany, but the status remained inactive.
Iodide I-131
go.drugbank.com/drugs/DB09293ApprovedInvestigationalPalliative effects may be observed in patients with advanced thyroid malignancy if the metastatic lesions take up iodine. … Therapeutic solutions of Sodium Iodide-131 are indicated for the treatment of hyperthyroidism and thyroid carcinomas that take up iodine.
Diazepam
go.drugbank.com/drugs/DB00829ApprovedIllicitInvestigationalVet approvedIts actions are mediated by enhancement of gamma-aminobutyric acid activity. … diazepam's storied history as a commonly used and effective medication for a variety of indications, contemporary advancements in the formulation and administration of the agent include the development and US
Deutivacaftor
go.drugbank.com/drugs/DB15141ApprovedInvestigational[L52275,A179677] Deutivacaftor was first approved by the US FDA in December 2024 in combination with two CFTR correctors - [tezacaftor] and [vanzacaftor] - for the treatment of patients with responsive
Hydrogenated soybean oil
go.drugbank.com/drugs/DB11302ApprovedAccording to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance. … Linolenic acid and stearic acids are contained in hydrogenated soybean oil, but hydrogenation results in reduced unsaturation in linolenic acid.
Triprolidine
go.drugbank.com/drugs/DB00427ApprovedFirst generation histamine H1 antagonist used in allergic rhinitis; asthma; and urticaria. It is a component of cough and cold medicines. It may cause drowsiness.
Mixtures: Overnight Cold and Flu, Overnight Cold and FluHepatitis A Vaccine
go.drugbank.com/drugs/DB10989ApprovedInvestigationalagainst the disease caused by infection with this virus. … [A199185,L12756] In the US, the approved vaccine is inactivated while live Hepatitis A vaccines are currently available in other countries.[L13392]
Products: AVAXIM 80 U PEDIATRIC, VAQTA VACCINE 25 u/0.5 ml