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Vecuronium
go.drugbank.com/drugs/DB01339ApprovedInvestigationalIts lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or … Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium.
Products: NORCURON 10 MG, BROMURODE VECURONIO 10 MGFidaxomicin
go.drugbank.com/drugs/DB08874ApprovedInvestigational[A190516] The FDA initially approved fidaxomicin in May 2011 for the treatment of _C. difficile_-associated diarrhea in adult patients over the age of 18. … Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months.
Products: DİFİCLİR 200 MG FİLM KAPLI TABLET, 20 ADETLamivudine
go.drugbank.com/drugs/DB00709ApprovedInvestigationalA reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring.
Mixtures: ABACAVIR E LAMIVUDINA SUN, ABACAVIR E LAMIVUDINA SUNCategories: Antivirals used in combination for the treatment of HIV infectionsCyclomethicone 5
go.drugbank.com/drugs/DB11244ApprovedCyclomethicone 5 is member of cyclomethicone, which are a group of liquid methyl siloxanes that have low viscosity and high volatility. … Cyclomethicones are cyclic in structure with a monomer backbone of one silicon and two oxygen atoms bonded together. Cyclomethicone 5 is used in cosmetic and personal products as a skin emollient.
Mixtures: Secret Key Tattoo Cover Cushion Spf50 Plus (23 Natural Beige), Secret Key Tattoo Cover Cushion Spf50 Plus (21 Light Beige)Lisocabtagene maraleucel
go.drugbank.com/drugs/DB16582ApprovedInvestigational[L31588] CAR T-cell therapy has changed the treatment of B-cell lymphomas, significantly increasing survival rates over standard therapy. … [A228493] Despite the adverse reactions, the majority of patients given lisocabtagene maraleucel reported an overall increase in quality of life over a 1 year period.
Deucravacitinib
go.drugbank.com/drugs/DB16650ApprovedInvestigationalUnlike other Janus kinase 1/2/3 inhibitors that bind to the conserved active domain of these non-receptor tyrosine kinases, deucravacitinib binds to the regulatory domain of TYK2 with high selectivity … [A246938, A246943] This selectivity towards TYK2 may lead to an improved safety profile of deucravacitinib, as nonselective JAK inhibitors are associated with a range of adverse effects such as altered
Products: SOTYKTU 6 mg film coated tabletsPregabalin
go.drugbank.com/drugs/DB00230ApprovedInvestigational[A187190] Although as per the FDA Label the mechanism of action has not been definitively characterized, there is evidence that pregabalin exerts its effects by binding to the α2δ subunit of voltage-dependent … [L1006,L7066] It may have dependence liability if misused but the risk appears to be highest in patients with current or past substance use disorders.[A31161]
Mixtures: PAGAMAX PLUS 150 MG/1 MG KAPSÜL ,60 KAPSÜL, PAGAMAX PLUS 75 MG/1 MG KAPSÜL ,60 KAPSÜLProducts: PREGABALIN SUN, PRECOBAL 75 MG/1 MG KAPSÜL, 60 ADETNiclosamide
go.drugbank.com/drugs/DB06803ApprovedInvestigationalVet approvedOver 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals. … Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases.
Categories: Compounds used in a research, industrial, or household settingProducts: YOMESAN 500 MG TABLET, 4 ADET, YOMESAN 500 MG TABLET, 500 ADETNaloxegol
go.drugbank.com/drugs/DB09049ApprovedInvestigationalThe advantage of naloxegol over the opioid antagonist naloxone is that its PEGylated structure allows for high selectivity for peripheral opioid receptors and lack of entry into the central nervous system … It was approved by the FDA in September 2014 and is indicated for the treatment of opioid-induced constipation (OIC) in adult patients with chronic non‑cancer pain.
Categories: Heterocyclic Compounds with 4 or More Rings, Compounds used in a research, industrial, or household settingDehydrocholic acid
go.drugbank.com/drugs/DB11622ApprovedThe use of dehydrocholic acid in over-the-counter products has been discontinued by Health Canada. … Dehydrocholic acid is a synthetic bile acid that was prepared from the oxidation of cholic acid with chromic acid [A33022]. It has been used for stimulation of biliary lipid secretion.